CXXC1

Gene Symbol CXXC1
Entrez Gene 30827
Alt Symbol 2410002I16Rik, 5830420C16Rik, CFP1, CGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1, hCGBP
Species Human
Gene Type protein-coding
Description CXXC finger protein 1
Other Description CXXC finger 1 (PHD domain)|CXXC-type zinc finger protein 1|CpG binding protein|DNA-binding protein with PHD finger and CXXC domain|PHD finger and CXXC domain-containing protein 1|cpG-binding protein|zinc finger, CpG binding-type containing 1
Swissprots Q9P2V7 Q96BC8 Q8N2W4 B2RC03 Q9P0U4
Accessions EAW62968 EAW62969 EAW62970 Q9P0U4 AA236925 AB031069 BAA96307 AB209883 BAD93120 AF149758 AAF37799 AK294645 BAG57822 AK314886 BAG37400 AL136862 CAB66796 BC002504 BC009188 BC014940 AAH14940 BC015733 AAH15733 BC029922 AAH29922 BX647189 DQ890630 ABM92247 DQ893798 ABM84724 XM_011525940 XP_011524242 XM_011525941 XP_011524243 NM_001101654 NP_001095124 NM_014593 NP_055408
Function Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. {ECO:0000269|PubMed:21407193}.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:12200428, ECO:0000269|PubMed:17355966}. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
Tissue Specificity Ubiquitous.

CXXC1 Antibody - 12585 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using CXXC1 Antibody.

CGBP (C-20) - sc-12339 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CGBP (C-20): sc-12339. Indirect, intracellular FCM analysis of fixed and permeabilized K-562 cells stained with CGBP (C-20) followed by FITC-conjugated donkey anti-goat IgG: sc-2024. Black line histogram represents the isotype control, normal goat IgG: sc-3887.

CGBP (H-120) - sc-25391 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CGBP (H-120): sc-25391. Western blot analysis of CGBP expression in non-transfected: sc-110760 (A) and human CGBP transfected: sc-112251 (B) 293 whole cell lysates and Jurkat nuclear extract (C).

CGBP (35) - sc-136419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CGBP (35): sc-136419. Western blot analysis of CGBP expression in K-562 whole cell lysate.

CGBP (N-21) - sc-12336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of CGBP expression in Jurkat (A,C) and K-562 (B,D) nuclear extracts. Antibodies tested include CGBP (N-21): sc-12336 (A,B) and CGBP (C-20): sc-12339 (C,D).

Anti-CGBP antibody - ab87288 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CGBP antibody (ab87288) at 1 µg/ml + THP-1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CGBP antibody - ab129433 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CGBP antibody (ab129433) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-CGBP antibody - ab113208 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
An antibody dectection detecting CGBP at 0.4 µg/ml in HeLa whole cell lysate by WB following IP.  Lane 1: IP with an antibody which recognizes an upstream epitope of CGBP  Lane 2: IP with ab113208 at 6µg/mg of lysate Lane 3: control IgG.  In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded.  Detection: Chemiluminescence with an exposure time of 30 seconds

Anti-CGBP antibody - ab13695 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CGBP antibody (ab13695) at 1/1000 dilution + Tissue lysates prepared from Human spleen at 15 µgExposure time :  15 minutes

Anti-CGBP antibody - ChIP Grade - ab56035 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CGBP antibody - ChIP Grade (ab56035) at 0.625 µg/ml + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CGBP antibody - N-terminal - ab189829 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of A549 cells using ab189829. Blue DAPI for nuclear staining.

Anti-CXXC1 / CGBP Antibody (aa325-354, AP) - LS-C208716 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa325-354, APC) - LS-C208718 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa325-354, Azide-free, HRP) - LS-C208721 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa325-354, Biotin) - LS-C208719 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa325-354, PE) - LS-C208722 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa325-354, FITC) - LS-C208720 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (C-Terminus) - LS-C31820 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Transfected 293T Cell Lysate

Anti-CXXC1 / CGBP Antibody (aa550-600) - LS-C289858 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa606-656) - LS-C289861 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa51-100) - LS-C151234 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CXXC1 / CGBP antibody Western Blot of Rat Testis.

Anti-CXXC1 / CGBP Antibody (aa325-354) - LS-C320701 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody - LS-C341887 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CXXC1 / CGBP Antibody (aa431-480) - LS-C101401 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CXXC1 / CGBP antibody LS-C101401 Western blot of THP-1 cell lysate.

Anti-CXXC1 / CGBP Antibody - LS-C655 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CGBP using antibody at 1:1000 dilution against 15 ug/lane of human spleen lysate. Immunoreactivity was determined using SuperSignal system (Pierce) and by exposing to the film for 15 minutes.
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