Gene Symbol | CXXC1 |
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Entrez Gene | 30827 |
Alt Symbol | 2410002I16Rik, 5830420C16Rik, CFP1, CGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1, hCGBP |
Species | Human |
Gene Type | protein-coding |
Description | CXXC finger protein 1 |
Other Description | CXXC finger 1 (PHD domain)|CXXC-type zinc finger protein 1|CpG binding protein|DNA-binding protein with PHD finger and CXXC domain|PHD finger and CXXC domain-containing protein 1|cpG-binding protein|zinc finger, CpG binding-type containing 1 |
Swissprots | Q9P2V7 Q96BC8 Q8N2W4 B2RC03 Q9P0U4 |
Accessions | EAW62968 EAW62969 EAW62970 Q9P0U4 AA236925 AB031069 BAA96307 AB209883 BAD93120 AF149758 AAF37799 AK294645 BAG57822 AK314886 BAG37400 AL136862 CAB66796 BC002504 BC009188 BC014940 AAH14940 BC015733 AAH15733 BC029922 AAH29922 BX647189 DQ890630 ABM92247 DQ893798 ABM84724 XM_011525940 XP_011524242 XM_011525941 XP_011524243 NM_001101654 NP_001095124 NM_014593 NP_055408 |
Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. {ECO:0000269|PubMed:21407193}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:12200428, ECO:0000269|PubMed:17355966}. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes. |
Tissue Specificity | Ubiquitous. |
CGBP CRISPR/Cas9 KO Plasmid (h) - sc-404704 from Santa Cruz Biotechnology
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CGBP HDR Plasmid (h) - sc-404704-HDR from Santa Cruz Biotechnology
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CGBP Double Nickase Plasmid (h) - sc-404704-NIC from Santa Cruz Biotechnology
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CGBP Double Nickase Plasmid (h2) - sc-404704-NIC-2 from Santa Cruz Biotechnology
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CGBP CRISPR Activation Plasmid (h) - sc-404704-ACT from Santa Cruz Biotechnology
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CGBP CRISPR Activation Plasmid (h2) - sc-404704-ACT-2 from Santa Cruz Biotechnology
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CGBP Lentiviral Activation Particles (h) - sc-404704-LAC from Santa Cruz Biotechnology
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CGBP Lentiviral Activation Particles (h2) - sc-404704-LAC-2 from Santa Cruz Biotechnology
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CGBP siRNA (h) - sc-35055 from Santa Cruz Biotechnology
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CGBP shRNA Plasmid (h) - sc-35055-SH from Santa Cruz Biotechnology
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CGBP shRNA (h) Lentiviral Particles - sc-35055-V from Santa Cruz Biotechnology
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CXXC1 RNAi - H00030827-R01 from Novus Biologicals
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MISSION® esiRNA - EHU052361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6839 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6839 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01261 from Sigma-Aldrich
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CXXC1 siRNA (Human) - CRH9348 from Cohesion Biosciences
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CXXC1 - MBS8218206 from MyBioSource
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shRNA set against Human CXXC1 (NM_014593.3) - SHH272449 from Creative biogene
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shRNA set against Human CXXC1(NM_014593.3) - SHG213787 from Creative biogene
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Human CXXC1 siRNA - orb269850 from Biorbyt
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CXXC1 shRNA Plasmid (Human) - CHH9348 from Cohesion Biosciences
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CXXC1 miRNA 3'UTR clone - MiUTR1H-02587 from Creative biogene
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CXXC1 miRNA 3'UTR clone - MiUTR3H-10438 from Creative biogene
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