TOB1

Gene Symbol TOB1
Entrez Gene 10140
Alt Symbol APRO6, PIG49, TOB, TROB, TROB1
Species Human
Gene Type protein-coding
Description transducer of ERBB2, 1
Other Description proliferation-inducing gene 49|protein Tob1|transducer of erbB-2 1
Swissprots B2R9T0 D3DTY3 Q4KMQ0 P50616
Accessions EAW94577 EAW94578 P50616 AA675891 AK313904 BAG36627 AY524047 AAS94256 BC031406 AAH31406 BC070493 AAH70493 BC098415 AAH98415 BT019380 AAV38187 BT019381 AAV38188 CR536487 CAG38726 CR541686 CAG46487 D38305 BAA07423 DA039934 DQ890837 ABM81763 DQ893992 ABM84918 DQ893993 ABM84919 NM_001243877 NP_001230806 NM_001243885 NP_001230814 NM_005749 NP_005740
Function Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. {ECO:0000269|PubMed:23236473, ECO:0000269|PubMed:8632892}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. {ECO:0000250}.
Tissue Specificity Ubiquitous.
Top Pathways RNA degradation

TOB1 CRISPR/Cas9 KO Plasmid (h) - sc-402842 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 HDR Plasmid (h) - sc-402842-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 Double Nickase Plasmid (h) - sc-402842-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 Double Nickase Plasmid (h2) - sc-402842-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 CRISPR Activation Plasmid (h) - sc-402842-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 CRISPR Activation Plasmid (h2) - sc-402842-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 Lentiviral Activation Particles (h) - sc-402842-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 Lentiviral Activation Particles (h2) - sc-402842-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TOB1 siRNA (h) - sc-37504 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TOB1 shRNA Plasmid (h) - sc-37504-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TOB1 shRNA (h) Lentiviral Particles - sc-37504-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU016361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21805 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21805 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TOB1 siRNA (Human) - CRH6841 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TOB1 - MBS8228903 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TOB1 (NM_005749.3) - SHH432620 from Creative biogene

Category siRNA
Species Reactivities Human

Human TOB1 siRNA - orb267343 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TOB1 shRNA Plasmid (Human) - CHH6841 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TOB1 miRNA 3'UTR clone - MiUTR3H-07761 from Creative biogene

Species Reactivities Human
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