SGPP2

Gene Symbol	SGPP2
Entrez Gene	130367
Alt Symbol	SPP2
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate phosphatase 2
Other Description	SPPase2|hSPP2|sphingosine 1-phosphate phosphohydrolase 2|sphingosine-1-phosphatase 2|sphingosine-1-phosphate phosphotase 2
Swissprots	Q8IWX5 Q8N8Q6 A3KPB4
Accessions	AAX88957 AAY24195 EAW70801 Q8IWX5 AF542512 AAN28731 AK096323 BAC04762 AK314322 BAG36970 BC106904 AAI06905 BC106905 AAI06906 BC114513 BC134342 AAI34343 XM_005246297 XP_005246354 NM_152386 NP_689599
Function	Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. {ECO:0000269|PubMed:12411432, ECO:0000269|PubMed:17113265}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12411432}; Multi-pass membrane protein {ECO:0000269|PubMed:12411432}.
Tissue Specificity	Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes. {ECO:0000269|PubMed:12411432}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Sphingosine 1 phosphate phosphatase 2 full length protein - ab165326 from Abcam Category Protein Source Wheat germ Species Human

SGPP2 Antibody Blocking Peptide - LS-E5721 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SGPP2 Antibody Blocking Peptide - LS-E16697 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Sphingosine 1 phosphate phosphatase 2 Protein - H00130367-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SGPP2-Antibody-N-term-Blocking-Peptide - BP18254a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SGPP2 Blocking Peptide - 33R-8562 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SGPP2 - H00130367-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SGPP2 - H00130367-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SGPP2 control peptide - AP05170CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Recombinant Sphingosine-1-Phosphate Phosphatase 2 (SGPP2) - RPE697Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SGPP2 Peptide (OEEG01187) - OEEG01187 from Aviva Systems Biology Category Peptide Prices $150.00 Sizes 50 µg Species Human

Sphingosine 1-Phosphate Phosphatase 2, Peptide - MBS396435 from MyBioSource Category Peptide Prices $195.00 Sizes 50 µg Species Human

SGPP2 Peptide, Human - M34GP14146H from Creative Peptides Category Peptide Source Synthetic. Species Human

SPP2 Peptide, Human - M34GP15083H from Creative Peptides Category Peptide Source Synthetic. Species Human

Sphingosine-1-phosphate phosphatase 2 (SGPP2), Recombinant Protein - MBS7093434 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more