FGF2

Gene Symbol	FGF2
Entrez Gene	2247
Alt Symbol	BFGF, FGF-2, FGFB, HBGF-2
Species	Human
Gene Type	protein-coding
Description	fibroblast growth factor 2 (basic)
Other Description	basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin
Swissprots	Q9UCS6 Q9UCS5 P09038 O00527 P78443 Q16443 Q7KZ11 Q7KZ72 A4LBB8 Q5PY50 Q9UC54
Accessions	AAB21432 ABO43041 ADL14514 CAA28027 CAA28028 CAA28029 CAA73868 EAX05222 P09038 AA256481 AB451321 BAG70135 AB451450 BAG70264 AY820133 AAV70487 BC111737 BC166646 AAI66646 BE439775 BP292299 BU501243 CN315083 J04513 AAA52531 M17599 AAA52534 M27968 AAA52448 S47380 AAD13853 NM_002006 NP_001997
Function	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269|PubMed:1721615, ECO:0000269|PubMed:8663044}.
Subcellular Location	Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57.
Tissue Specificity	Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. {ECO:0000269|PubMed:1417798, ECO:0000269|PubMed:1721615}.
Top Pathways	Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FGF2 ORF Clone(NM_002006.4) - CDCL163470 from Creative Biomart Species Human Accession NM_002006.4

Human FGF2 ORF clone(NM_002006.4) - CDCG003815 from Creative Biomart Species Human Accession NM_002006.4

Human FGF2 ORF clone - CDCL108055 from Creative Biomart Species Human Accession NM_002006

Human FGF2 ORF clone - CDCL108056 from Creative Biomart Species Human Accession NM_002006

Mouse FGF2 ORF clone - CDCL108057 from Creative Biomart Species Human Accession NM_002006

Mouse FGF2 ORF clone - CDCL108058 from Creative Biomart Species Human Accession NM_002006

Human bFGF/FGF2 Gene ORF cDNA clone in cloning vector - HG10014-M from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10014-CM from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10014-NH from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10014-ACR from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10014-CY from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10014-CH from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid - HG10014-UT from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10014-NY from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10014-ACG from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10014-NF from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10014-CF from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10014-NM from Sino Biological Species Human

Human FGF2 ORF clone(NM_002006.4) - CDCG003815 from Creative biogene Species Human

Human FGF 2 Gene - orb91628 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10014-ANG from Sino Biological Species Human

Human bFGF/FGF2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10014-ANR from Sino Biological Species Human

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