EIF2S1

Gene Symbol	EIF2S1
Entrez Gene	1965
Alt Symbol	EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Other Description	eIF-2-alpha|eukaryotic translation initiation factor 2 subunit 1|eukaryotic translation initiation factor 2 subunit alpha
Swissprots	P05198
Accessions	EAW80933 EAW80934 P05198 AK297244 BAG59724 AK312442 BAG35351 BC002513 AAH02513 BX161521 CAD61953 D28379 BAA05745 DQ892151 ABM83077 DQ895347 ABM86273 J02645 AAA52373 U26032 NM_004094 NP_004085
Function	Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Subcellular Location	Cytoplasmic granule {ECO:0000250}. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). {ECO:0000250}.
Top Pathways	Protein processing in endoplasmic reticulum, RNA transport, Hepatitis C, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EIF2S1 (phospho S51) peptide - ab199382 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human EIF2S1 full length protein - ab123468 from Abcam Category Protein Source E. coli Species Human

Human EIF2S1 peptide - ab26881 from Abcam Category Peptide

EIF2S1 Antibody Blocking Peptide - LS-E2448 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF2S1 Antibody Blocking Peptide - LS-E14792 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

eIF2 alpha/EIF2S1 Recombinant Protein - H00001965-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

eIF2 alpha/EIF2S1 Protein - NBP1-44467 from Novus Biologicals Category Protein Prices $369.00 Sizes 50 µg Species Human

EIF2S1-Antibody-N-term-Blocking-peptide - BP13469a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

eIF2A peptide-phospho Ser51 (phospho and non-phospho pair) - GTX25243 from GeneTex Category Peptide Prices $329.00 Sizes 1 pack Species Human

EIF2S1 Protein (OPPA02293) - OPPA02293 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human EIF2S1 protein - orb81080 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

EIF2S1 peptide - orb217239 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Zebrafish, Cat

EIF2S1 peptide - orb217238 from Biorbyt Category Peptide Prices $306.00, $519.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Zebrafish, Cat

EIF2S1 Blocking Peptide - 33R-7946 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF2S1 Blocking Peptide - 33R-9903 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF2S1 protein (His tag) - 80R-1344 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

EIF2S1 (phospho-Ser51) Blocking Peptide - abx062569 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Pig, Zebrafish

EIF2S1 Blocking Peptide - abx062570 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Pig, Zebrafish

EIF2A / EIF2S1 (1-315, His-tag) - AR09518PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

EIF2A / EIF2S1 (1-315, His-tag) - AR09518PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

EIF2S1, 1-315aa, Human, His tag, E.coli - 01-1768-2S1 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

EIF2S1 fusion protein - Ag1645 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human EIF2S1 Protien - BP001959-PRO-845 from Syd Labs Category Protein Prices $160.00, $4,800.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

EIF2S1, 1-315aa, Recombinant Protein - GWB-P1457A from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

EIF2S1 Human Protein - GWB-BSP468 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

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