SCN11A

Gene Symbol SCN11A
Entrez Gene 11280
Alt Symbol FEPS3, HSAN7, NAV1.9, NaN, PN5, SCN12A, SNS-2
Species Human
Gene Type protein-coding
Description sodium channel, voltage gated, type XI alpha subunit
Other Description peripheral nerve sodium channel 5|sensory neuron sodium channel 2|sodium channel protein type 11 subunit alpha|sodium channel protein type XI subunit alpha|sodium channel, voltage-gated, type XI, alpha polypeptide|sodium channel, voltage-gated, type XI, alpha subunit|sodium channel, voltage-gated, type XII, alpha polypeptide|voltage-gated sodium channel subunit alpha Nav1.9
Swissprots Q8NDX3 C9JR31 Q68K15 Q9UI33 Q9UHM0 A6NN05 C9JD48 Q9UHE0
Accessions AAD53407 AAO85712 CAJ84379 EAW64544 EAW64545 EAW64546 Q9UI33 AF109737 AAF24976 AF150882 AAF24980 AF188679 AAF17480 AJ417790 CAD10507 AY686224 AAT95434 BC172234 AAI72234 XM_011533320 XP_011531622 XM_011533321 XP_011531623 XM_011533322 XP_011531624 NM_001287223 NP_001274152 NM_014139 NP_054858
Function This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization. {ECO:0000269|PubMed:10580103, ECO:0000269|PubMed:12384689}.
Subcellular Location Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta. {ECO:0000269|PubMed:10623608, ECO:0000269|PubMed:15302875}.

Na + CP type XIα (D-13) - sc-103058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Na + CP type XIα (N-12) - sc-103060 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SCN11A antibody - ab65160 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab65160 staining SCN11A in human sperm cells by Immunocytochemistry/ Immunofluorescence.Sperm cells were washed, re-suspended in phosphate-buffered saline and smeared onto poly-L-lysine-coated slides. Spermatozoa were then fixed by incubation in cold methanol (-20°C) for 20 minutes. Slides were washed three times for 10 minutes with PBS and incubated with 2% BSA in PBS for 30 minutes to block non-specific sites. Test slides were incubated with ab65160 at a 1/100 dilution. Samples were washed three times in PBS, and incubated for 60 minutes with appropriate FITC-conjugated secondary antibodies. Slides were further washed in PBS, mounted using Vectashield and examined with a Olympus BX-51 fluorescence microscopy using a 100× immersion objective.

Anti-SCN11A antibody - ab198859 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling SCN11A with ab198859 at 1/40 dilution.

Anti-SCN11A antibody - ab56959 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56959 SCN11A antibody at 1ug/ml.

Anti-SCN11A / Nav1.9 Antibody - LS-C144739 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCN11A Antibody - NBP1-30836 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCN11A Antibody - NBP1-82600 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SCN11A Antibody [NBP1-82600] - Staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells.

SCN11A Antibody (6E1) - H00011280-M04 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E1
ELISA: SCN11A Antibody (6E1) [H00011280-M04] - Detection limit for recombinant GST tagged SCN11A is approximately 0.03ng/ml as a capture antibody.

Monoclonal Anti-SCN11A antibody produced in mouse - WH0011280M4 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E1
<B>Immunoblotting</B><BR/>Monoclonal Anti-SCN11A, <B>Cat. No. WH0011280M4</B> used at the antibody concentration: 1 μg/mL. Specific band of ~33.37 kDa using immunogen protein lysate.

Anti-SCN11A antibody produced in rabbit - HPA036746 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SCN11A: <B>Cat. No. HPA036746</B>: Immunohistochemical staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells.

Anti-Sodium Channel NaV1.9 antibody produced in rabbit - S2196 from Sigma-Aldrich

Prices $279.00, $571.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-Na<SUB>v</SUB>1.9: <B>Cat. No. S2196</B>: Immunohistochemical staining of formalin frozen Rat embryo dorsal root ganglion (DRG) sections with Anti-Na<SUB>v</SUB>1.9 antibody. (A) Cells within the DRG were stained (see solid line frame enlarged in B) as well as fibers and the area of entry of dorsal root into the spinal cord (see dashed line frame enlarged in C). DAPI is used as the counterstain.

Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse - SAB1404926 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B10
<B>Immunoblotting</B><BR/>Monoclonal Anti-SCN11A: <B>Cat. No. SAB1404926</B>: Antibody concentration: 1 μg/mL. Specific band of ~33.4 kDa using immunogen protein lysate.

SCN11A-Antibody-monoclonal-M04 - AT3791a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 60
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33 KDa) .

SCN11A antibody - orb100937 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed and paraffin embedded human placenta tissue (Dilution at:1:200) using SCN11A antibody

SCN11A antibody (FITC) - orb103446 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

SCN11A / PN5 antibody - AP55283SU-N from Acris Antibodies

Prices $460.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

SCN11A / PN5 antibody - H00011280-M02 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B10

SCN11A / PN5 antibody - H00011280-M04 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E1
Detection limit for recombinant GST tagged SCN11A is approximately 0.03ng/ml as a capture antibody.

SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Antibody - 37231 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using #37231 at dilution 1/40.

SCN11A Antibody - 37235 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #37235 at dilution 1/40.

SCN11A, Monoclonal Antibody - MBS648240 from MyBioSource

Prices $580.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E1

SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Polyclonal Antibody - ESAP13100 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human lung cancer using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Polyclonal Antibody at dilution of 1:40

SCN11A Polyclonal Antibody - ESAP13105 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human breast cancer using SCN11A Polyclonal Antibody at dilution of 1:40

SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A Polyclonal Antibody - ESAP16406 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human esophagus cancer using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A Polyclonal Antibody at dilution of 1:50
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