Gene Symbol | S100A1 |
---|---|
Entrez Gene | 6271 |
Alt Symbol | S100, S100-alpha, S100A |
Species | Human |
Gene Type | protein-coding |
Description | S100 calcium binding protein A1 |
Other Description | S-100 protein alpha chain|S-100 protein subunit alpha|S100 alpha|S100 calcium-binding protein A1|S100 protein, alpha polypeptide|protein S100-A1 |
Swissprots | B2R5D9 Q5T7Y3 P23297 |
Accessions | CAY39334 EAW53301 EAW53302 P23297 AB451316 BAG70130 AB451446 BAG70260 AK126904 AK312152 BAG35086 BC014392 AAH14392 BC035791 BC072006 BC094843 BT006938 AAP35584 X58079 CAA41107 NM_006271 NP_006262 |
Function | Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. {ECO:0000269|PubMed:22399290}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. |
S-100 α chain CRISPR/Cas9 KO Plasmid (h) - sc-402065 from Santa Cruz Biotechnology
|
||||||||
S-100 α chain HDR Plasmid (h) - sc-402065-HDR from Santa Cruz Biotechnology
|
||||||||
S-100 α chain Double Nickase Plasmid (h) - sc-402065-NIC from Santa Cruz Biotechnology
|
||||||||
S-100 α chain Double Nickase Plasmid (h2) - sc-402065-NIC-2 from Santa Cruz Biotechnology
|
||||||||
S-100 α chain CRISPR Activation Plasmid (h) - sc-402065-ACT from Santa Cruz Biotechnology
|
||||||||
S-100 α chain CRISPR Activation Plasmid (h2) - sc-402065-ACT-2 from Santa Cruz Biotechnology
|
||||||||
S-100 α chain Lentiviral Activation Particles (h) - sc-402065-LAC from Santa Cruz Biotechnology
|
||||||||
S-100 α chain Lentiviral Activation Particles (h2) - sc-402065-LAC-2 from Santa Cruz Biotechnology
|
||||||||
S-100 α chain siRNA (h) - sc-43354 from Santa Cruz Biotechnology
|
||||||||
S-100 α chain shRNA Plasmid (h) - sc-43354-SH from Santa Cruz Biotechnology
|
||||||||
S-100 α chain shRNA (h) Lentiviral Particles - sc-43354-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU114601 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18779 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18779 from Sigma-Aldrich
|
||||||||
S100A1 siRNA (Human) - CRH4219 from Cohesion Biosciences
|
||||||||
S100A1 RNAi - H00006271-R01 from Novus Biologicals
|
||||||||
S100A1 - MBS8205453 from MyBioSource
|
||||||||
shRNA set against Human S100A1 (NM_006271.1) - SHH401068 from Creative biogene
|
||||||||
shRNA set against Human S100A1(NM_006271.1) - SHR202758 from Creative biogene
|
||||||||
S100A1 shRNA Plasmid (Human) - CHH4219 from Cohesion Biosciences
|
||||||||
S100A1 miRNA 3'UTR clone - MiUTR1H-09102 from Creative biogene
|