Eed

Gene Symbol Eed
Entrez Gene 13626
Alt Symbol ENSMUSG00000039373, l(7)5Rn, l7Rn5, lusk
Species Mouse
Gene Type protein-coding
Description embryonic ectoderm development
Other Description lethal, Chr 7, Rinchik 5|polycomb protein EED
Swissprots P97462 Q921E6
Accessions EDL06770 EDL06771 Q921E6 AK016228 BAB30159 AK053947 AK077664 BAC36938 AK087924 AK131976 BAE20916 AK133890 BAE21915 AK213110 BC012966 AAH12966 BQ899891 CJ200028 U78103 AAB38319 U97675 AAC53302 XM_006507341 XP_006507404 XR_869658 XR_869659 NM_021876 NP_068676
Function Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark (By similarity). The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. Plays a role in X chromosome inactivation (XCI), in which one of the two X chromosomes in female mammals is transcriptionally silenced to equalize X-linked gene dosage with XY males. Required for stable maintenance of XCI in both embryonic and extraembryonic tissues. May prevent transcriptio
Subcellular Location Nucleus. Chromosome. Note=Localizes to the inactive X chromosome in cells of the early embryo and in stem cells of the extraembryonic trophectoderm lineage. Recruitment to the inactive X-chromosome requires XIST.
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, muscle, ovary, spleen and testis. Expressed throughout the brain. {ECO:0000269|PubMed:17259173, ECO:0000269|PubMed:8805699, ECO:0000269|PubMed:9234727}.

Anti-EED antibody produced in rabbit - SAB2106374 from Sigma-Aldrich

Prices $341.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EED: <B>Cat. No. SAB2106374</B>: Western blot analysis of Eed in Mouse Brain with Eed (embryonic ectoderm development) antibody against the N terminal of Eed (50 μg) antibody at 1.0 μg/mL.

Eed antibody - N-terminal region (ARP35696_P050) - ARP35696_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Mouse-Eed-Antibody-N-term - AP21106a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from mouse brain tissue lysate, using Eed Antibody (N-term)(Cat. #AP21106a). AP21106a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Mouse-Eed-Antibody-Center - AP21210c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Eed Antibody (Center) at 1:1000 dilution Lane 1: A431 whole cell lysates Lane 2: NIH/3T3 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Embryonic Ectoderm Development Antibody - abx112280 from Abbexa

Host Rabbit
Clonality Polyclonal

Eed Antibody - GWB-MM158E from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit

RIPAb+™ EED - RIP Validated Antibody and Primer Set - 03-196 from EMD Millipore

Prices $389.00
Sizes 10 assays 10 assays per set. recommended use: ~5 μg of antibody per rip . (dependent upon biological context)
Host Mouse
Clonality Monoclonal

Anti-EED Antibody, clone AA19 - 05-1320 from EMD Millipore

Prices $367.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AA19

EED Antibody - CSB-PA007408GA01HU from Cusabio

Host Rabbit

Eed Antibody - N-terminal region (OAAB19066) - OAAB19066 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Eed Antibody - middle region (OAAB19170) - OAAB19170 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Eed, Polyclonal Antibody - MBS9204757 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Eed, Polyclonal Antibody - MBS9201630 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Anti-EED antibody produced in rabbit - SAB2108394 from Sigma-Aldrich

Prices $351.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EED: <B>Cat. No. SAB2108394</B>: Western blot analysis of Eed in Mouse Brain with Eed (embryonic ectoderm development) antibody against the N terminal of Eed (50 μg) antibody at 1.0 μg/mL.

EED Antibody (F53203) - F53203 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 80 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 400 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot testing of EED antibody at 1:1000 dilution. Lane 1: A431 lysate; 2: NIH3T3 lysate; Predicted molecular weight: 50 kDa (isoform 1), 53 kDa (isoform 2), 46 kDa (isoform 3).

Eed Antibody (F53077) - F53077 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 80 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 400 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from mouse brain tissue lysate using Eed antibody diluted at 1:1000. Predicted molecular weight: 50 kDa (isoform 1), 53 kDa (isoform 2), 46 kDa (isoform 3).

Eed antibody - N-terminal region : Biotin (ARP35696_P050-Biotin) - ARP35696_P050-Biotin from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Eed antibody - N-terminal region : FITC (ARP35696_P050-FITC) - ARP35696_P050-FITC from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Eed antibody - N-terminal region : HRP (ARP35696_P050-HRP) - ARP35696_P050-HRP from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Eed antibody - orb306484 from Biorbyt

Host Rabbit
Clonality Polyclonal
Search more