| Gene Symbol |
MRC1
|
| Entrez Gene |
4360
|
| Alt Symbol |
CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mannose receptor, C type 1
|
| Other Description |
C-type lectin domain family 13 member D|macrophage mannose receptor 1|macrophage mannose receptor 1-like protein 1|mannose receptor, C type 1-like 1
|
| Swissprots |
Q5VSJ2 Q5VSK2 A5PKW3 P22897
|
| Accessions |
AAA60389 ACA06020 CAH70733 CAH71176 CAI15339 CCQ43179 P22897 AK297044 BAG59571 AK308132 AK308167 AV659122 BC016003 BC142642 AAI42643 BC146838 AAI46839 BU198859 DC296466 DQ663787 ABG47462 J05550 AAA59868 X55635 NM_001009567 NM_002438 NP_002429
|
| Function |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
|
| Subcellular Location |
Endosome membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. Cell membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}.
|
| Top Pathways |
Phagosome, Tuberculosis
|