Gene Symbol | MRC1 |
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Entrez Gene | 4360 |
Alt Symbol | CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1 |
Species | Human |
Gene Type | protein-coding |
Description | mannose receptor, C type 1 |
Other Description | C-type lectin domain family 13 member D|macrophage mannose receptor 1|macrophage mannose receptor 1-like protein 1|mannose receptor, C type 1-like 1 |
Swissprots | Q5VSJ2 Q5VSK2 A5PKW3 P22897 |
Accessions | AAA60389 ACA06020 CAH70733 CAH71176 CAI15339 CCQ43179 P22897 AK297044 BAG59571 AK308132 AK308167 AV659122 BC016003 BC142642 AAI42643 BC146838 AAI46839 BU198859 DC296466 DQ663787 ABG47462 J05550 AAA59868 X55635 NM_001009567 NM_002438 NP_002429 |
Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. |
Subcellular Location | Endosome membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. Cell membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. |
Top Pathways | Phagosome, Tuberculosis |
Mannose Receptor Antibody - 12981 from Cell Signaling Technology
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CD206 (D-1) - sc-376108 from Santa Cruz Biotechnology
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CD206 (C-10) - sc-376232 from Santa Cruz Biotechnology
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CD206 (H-300) - sc-48758 from Santa Cruz Biotechnology
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CD206 (15-2) - sc-58986 from Santa Cruz Biotechnology
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CD206 (C-20) - sc-34577 from Santa Cruz Biotechnology
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CD206 (6A598) - sc-70585 from Santa Cruz Biotechnology
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CD206 (3H1994) - sc-70586 from Santa Cruz Biotechnology
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Anti-Mannose Receptor antibody - ab64693 from Abcam
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Anti-Mannose Receptor antibody - ab129666 from Abcam
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Anti-Mannose Receptor antibody [15-2] - ab8918 from Abcam
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Anti-Mannose Receptor antibody [15-2] (Biotin) - ab8919 from Abcam
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Anti-Mannose Receptor antibody [5C11] - ab117644 from Abcam
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Anti-Mannose Receptor antibody [EPR6828(B)] - ab125028 from Abcam
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Anti-Mannose Receptor antibody [EPR6828(B)] (HRP) - ab195193 from Abcam
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Anti-Mannose Receptor antibody [MM0820-48L31] - ab201927 from Abcam
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Anti-Mannose Receptor / CD206 Antibody - LS-C14384 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody - LS-C16310 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody (Biotin) - LS-C16311 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody - LS-C25397 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody (aa19-1383) - LS-C35882 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody - LS-C124034 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody - LS-C124033 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody (clone MR5D3) - LS-C124035 from LifeSpan Bioscience
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Anti-Mannose Receptor / CD206 Antibody (clone 7-450) - LS-C58102 from LifeSpan Bioscience
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