Gene Symbol | FGF21 |
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Entrez Gene | 26291 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 21 |
Other Description | - |
Swissprots | Q8N683 Q9NSA1 |
Accessions | ABI75345 CAC41219 CBL54507 CBY65805 CBY65875 EAW52401 EAW52402 Q9NSA1 AB021975 BAA99415 AY359086 AAQ89444 BC018404 AAH18404 DQ891786 ABM82712 DQ894970 ABM85896 XM_005258731 XP_005258788 NM_019113 NP_061986 |
Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. {ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:17623664}. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF21 Lysate(Denatured) - H00026291-T01 from Acris Antibodies
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FGF21 overexpression lysate - LY412740 from Acris Antibodies
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FGF21 293 Cell Lysate - 406223 from ABBIOTEC
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FGF-21 Overexpression Lysate (Denatured) - H00026291-T01 from Novus Biologicals
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FGF-21 Overexpression Lysate (Native) - NBL1-10695 from Novus Biologicals
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FGF21 Over-expression Lysate Product - GWB-204572 from Genway Biotech
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Cynomolgus FGF21 / Fibroblast Growth Factor 21 HEK293 Cell Lysate (WB positive control) - 90843-C08HL-300 from Sino Biological
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FGF-21 Overexpression Lysate (Denatured) - H00026291-T02 from Novus Biologicals
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Panoply™ Human FGF21 Knockdown Stable Cell Line - CSC-DC005705 from Creative biogene
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FGF21 Knockout Cell Line-HeLa - CSC-RT2045 from Creative biogene
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FGF21 KO Cell Lysate-HeLa - CLKO-1906 from Creative biogene
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