FGF21

Gene Symbol FGF21
Entrez Gene 26291
Alt Symbol -
Species Human
Gene Type protein-coding
Description fibroblast growth factor 21
Other Description -
Swissprots Q8N683 Q9NSA1
Accessions ABI75345 CAC41219 CBL54507 CBY65805 CBY65875 EAW52401 EAW52402 Q9NSA1 AB021975 BAA99415 AY359086 AAQ89444 BC018404 AAH18404 DQ891786 ABM82712 DQ894970 ABM85896 XM_005258731 XP_005258788 NM_019113 NP_061986
Function Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. {ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:17623664}.
Subcellular Location Secreted {ECO:0000305}.
Top Pathways Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton

Active human FGF21 full length protein - ab108556 from Abcam

Category Protein
Prices $315.00
Sizes 10 µg
Source HEK 293 cells
Species Human
ERK and FRS2alpha phosphorylation induced by FGF21 in bKlotho expressing cells. bKlotho expressing cells were serum starved for 16hr and then stimulated with hFGF21-His (competitor), ab108556 (FGF 21-Fc), mCD137-Fc (Fc control) and FGF-b (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 & total ERK1/2 were used for immunoblotting. Lane 1: 1 µg/ml hFGF21-His (competitor) Lane 2: 2.2 µg/ml ab108556 (hFGF21-Fc) Lane 3: 2.2 µg/ml mCD137-Fc Lane 4: 100 ng/µl FGF-b Lane 5: control (non-treated)

Active human FGF21 full length protein - ab200233 from Abcam

Category Protein
Prices $101.00
Sizes 5 µg
Source E. coli
Species Human

Active human FGF21 full length protein - ab191768 from Abcam

Category Protein
Prices $192.00
Sizes 20 µg
Source E. coli
Species Human

Human FGF21 full length protein - ab133137 from Abcam

Category Protein
Source E. coli
Species Human
SDS-PAGE analysis of ab133137.

Human FGF21 full length protein - ab54141 from Abcam

Category Protein
Source E. coli
Species Human

Human FGF21 full length protein - ab108578 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Human FGF21 full length protein - ab185602 from Abcam

Category Protein
Source E. coli
Species Human

Human FGF21 full length protein - ab108571 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Human FGF21 peptide - ab66562 from Abcam

Category Peptide

Human FGF21 peptide - ab66563 from Abcam

Category Peptide

Mouse FGF21 full length protein - ab64004 from Abcam

Category Protein
Source E. coli
Species Mouse
LANE 1. M.W. marker – 14, 21, 31, 45, 66, 97 kDa. LANE 2. reduced and heated sample, 5µg/lane. LANE 3. non-reduced and non-heated sample, 5µg/lane.

Mouse FGF21 full length protein - ab63277 from Abcam

Category Protein
Source E. coli
Species Mouse
LANES: 1. MW marker – 14, 21, 31, 45, 66, 97 kDa 2. reduced and heated sample, 5µg/lane 3. non-reduced and non-heated sample, 5µg/lane

Mouse FGF21 full length protein - ab108554 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse

Mouse FGF21 full length protein - ab108570 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse

Mouse FGF21 full length protein - ab108580 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse

FGF21 Antibody Blocking Peptide - LS-E26480 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FGF21 Antibody Blocking Peptide - LS-E20001 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FGF-21 Protein - NBP2-35023 from Novus Biologicals

Category Protein
Prices $69.00, $149.00, $2,669.00
Sizes 5 µg, 25 µg, 1 mg
Source E. coli
Species Human
SDS-Page: Human FGF-21 Protein [NBP2-35023]

FGF-21 Recombinant Protein - H00026291-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

FGF-21 Recombinant Protein - P3476 from Novus Biologicals

Category Protein
Prices $469.00
Sizes 100 µg
Species Human
SDS-Page: FGF21 Protein [P3476]

Recombinant Human FGF-21 Protein - NBC1-19061 from Novus Biologicals

Category Protein
Prices $229.00
Sizes 100 µg
Source E.coli
Species Human
Western Blot: FGF21 Protein [NBC1-19061] - 21.6 kDa (202 aa) (Real molecular size on SDS-PAGE will be shift up)

FGF-21 Recombinant Protein - P4382 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 20 µg
Species Human

FGF-21 Protein - NBP1-99324 from Novus Biologicals

Category Protein
Species Human

Recombinant Human FGF-21 Protein - NBP1-99730 from Novus Biologicals

Category Protein
Prices $595.00
Sizes 100 µg
Source E. coli
Species Human

Recombinant Human FGF-21 Protein - NBC1-22610 from Novus Biologicals

Category Protein
Prices $229.00
Sizes 100 µg
Species Human
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