PSMB4

Gene Symbol PSMB4
Entrez Gene 5692
Alt Symbol HN3, HsN3, PROS-26, PROS26
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, beta type, 4
Other Description 26 kDa prosomal protein|hsBPROS26|macropain beta chain|multicatalytic endopeptidase complex beta chain|proteasome beta chain|proteasome chain 3|proteasome subunit HsN3|proteasome subunit beta type-4|proteasome subunit, beta type, 4
Swissprots P31148 Q6IBI4 Q969L6 B2R9L3 Q5SZS5 P28070
Accessions EAW53442 P28070 AK294149 BAG57474 AK313825 BAG36560 BC000331 BC008314 BC010088 BC010098 BC011768 BC012168 BC017307 BC017451 BC017486 BT006917 AAP35563 CR456820 CAG33101 D26600 BAA05647 DQ890748 ABM81674 DQ892020 ABM82946 DQ895212 ABM86138 S71381 AAB31085 NM_002796 NP_002787
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. {ECO:0000250, ECO:0000269|PubMed:12097147}.
Subcellular Location Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
Top Pathways Proteasome

PSMB4-Over-expression-Lysate - LY10119a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PSMB4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PSMB4 gene (Lane 2, Cat. #LY10119a).

PSMB4 overexpression lysate - LY419106 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

PSMB4 293 Cell Lysate - 408937 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Proteasome subunit beta type 4 Overexpression Lysate (Native) - NBL1-14879 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Proteasome subunit beta type 4 Overexpression Lysate [NBL1-14879] - Left: control (empty vector transfected control cell lysate); right: NBL1-14879. Antibody: DDK antibody.

PSMB4 Over-expression Lysate Product - GWB-84F132 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human PSMB4 Knockdown Stable Cell Line - CSC-DC012589 from Creative biogene

Category Cell Line
Species Human
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