PSMB4

Gene Symbol PSMB4
Entrez Gene 5692
Alt Symbol HN3, HsN3, PROS-26, PROS26
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, beta type, 4
Other Description 26 kDa prosomal protein|hsBPROS26|macropain beta chain|multicatalytic endopeptidase complex beta chain|proteasome beta chain|proteasome chain 3|proteasome subunit HsN3|proteasome subunit beta type-4|proteasome subunit, beta type, 4
Swissprots P31148 Q6IBI4 Q969L6 B2R9L3 Q5SZS5 P28070
Accessions EAW53442 P28070 AK294149 BAG57474 AK313825 BAG36560 BC000331 BC008314 BC010088 BC010098 BC011768 BC012168 BC017307 BC017451 BC017486 BT006917 AAP35563 CR456820 CAG33101 D26600 BAA05647 DQ890748 ABM81674 DQ892020 ABM82946 DQ895212 ABM86138 S71381 AAB31085 NM_002796 NP_002787
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. {ECO:0000250, ECO:0000269|PubMed:12097147}.
Subcellular Location Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
Top Pathways Proteasome

PSMB4 CRISPR/Cas9 KO Plasmid (h) - sc-410964 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 HDR Plasmid (h) - sc-410964-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 Double Nickase Plasmid (h) - sc-410964-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 Double Nickase Plasmid (h2) - sc-410964-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 CRISPR Activation Plasmid (h) - sc-410964-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 CRISPR Activation Plasmid (h2) - sc-410964-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 Lentiviral Activation Particles (h) - sc-410964-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 Lentiviral Activation Particles (h2) - sc-410964-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMB4 siRNA (h) - sc-76269 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSMB4 shRNA Plasmid (h) - sc-76269-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSMB4 shRNA (h) Lentiviral Particles - sc-76269-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Proteasome subunit beta type 4 RNAi - H00005692-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU025191 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17601 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17601 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PSMB4 siRNA (Human) - CRH3839 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PSMB4 (NM_002796.2) - SHH385192 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PSMB4(NM_002796.2) - SHR147408 from Creative biogene

Category siRNA
Species Reactivities Human

Human PSMB4 siRNA - orb264341 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PSMB4 shRNA Plasmid (Human) - CHH3839 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PSMB4 miRNA 3'UTR clone - MiUTR1H-08380 from Creative biogene

Species Reactivities Human
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