| Gene Symbol |
CISD1
|
| Entrez Gene |
55847
|
| Alt Symbol |
C10orf70, MDS029, ZCD1, mitoNEET
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CDGSH iron sulfur domain 1
|
| Other Description |
CDGSH iron sulfur domain-containing protein 1|CDGSH iron-sulfur domain-containing protein 1|zinc finger CDGSH-type domain 1|zinc finger, CDGSH-type domain 1
|
| Swissprots |
Q9NZ45 Q1X902
|
| Accessions |
EAW54162 EAW54163 EAW54164 EAW54165 EAW54166 Q9NZ45 AF220049 AAF67642 AI025360 AK312017 BAG34955 AY960578 AAY32336 BC005962 AAH05962 BC007043 AAH07043 BC008474 AAH08474 BC059168 AAH59168 DA417986 HQ448690 ADQ33168 NM_018464 NP_060934
|
| Function |
Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. {ECO:0000250, ECO:0000269|PubMed:17584744, ECO:0000269|PubMed:17766440}.
|
| Subcellular Location |
Mitochondrion outer membrane {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}; Single- pass type III membrane protein {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}.
|
| Tissue Specificity |
Expression is reduced in cells derived from cystic fibrosis patients. {ECO:0000269|PubMed:18047834}.
|