Gene Symbol | CISD1 |
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Entrez Gene | 55847 |
Alt Symbol | C10orf70, MDS029, ZCD1, mitoNEET |
Species | Human |
Gene Type | protein-coding |
Description | CDGSH iron sulfur domain 1 |
Other Description | CDGSH iron sulfur domain-containing protein 1|CDGSH iron-sulfur domain-containing protein 1|zinc finger CDGSH-type domain 1|zinc finger, CDGSH-type domain 1 |
Swissprots | Q9NZ45 Q1X902 |
Accessions | EAW54162 EAW54163 EAW54164 EAW54165 EAW54166 Q9NZ45 AF220049 AAF67642 AI025360 AK312017 BAG34955 AY960578 AAY32336 BC005962 AAH05962 BC007043 AAH07043 BC008474 AAH08474 BC059168 AAH59168 DA417986 HQ448690 ADQ33168 NM_018464 NP_060934 |
Function | Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. {ECO:0000250, ECO:0000269|PubMed:17584744, ECO:0000269|PubMed:17766440}. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}; Single- pass type III membrane protein {ECO:0000269|PubMed:17376863, ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17905743, ECO:0000269|PubMed:18047834}. |
Tissue Specificity | Expression is reduced in cells derived from cystic fibrosis patients. {ECO:0000269|PubMed:18047834}. |
mitoNEET CRISPR/Cas9 KO Plasmid (h) - sc-417601 from Santa Cruz Biotechnology
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mitoNEET HDR Plasmid (h) - sc-417601-HDR from Santa Cruz Biotechnology
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mitoNEET Double Nickase Plasmid (h) - sc-417601-NIC from Santa Cruz Biotechnology
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mitoNEET Double Nickase Plasmid (h2) - sc-417601-NIC-2 from Santa Cruz Biotechnology
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mitoNEET CRISPR Activation Plasmid (h) - sc-417601-ACT from Santa Cruz Biotechnology
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mitoNEET CRISPR Activation Plasmid (h2) - sc-417601-ACT-2 from Santa Cruz Biotechnology
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mitoNEET Lentiviral Activation Particles (h) - sc-417601-LAC from Santa Cruz Biotechnology
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mitoNEET Lentiviral Activation Particles (h2) - sc-417601-LAC-2 from Santa Cruz Biotechnology
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mitoNEET siRNA (h) - sc-90615 from Santa Cruz Biotechnology
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mitoNEET shRNA Plasmid (h) - sc-90615-SH from Santa Cruz Biotechnology
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mitoNEET shRNA (h) Lentiviral Particles - sc-90615-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6140 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6140 from Sigma-Aldrich
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CISD1 siRNA (Human) - CRJ0968 from Cohesion Biosciences
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CISD1 - MBS8206275 from MyBioSource
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shRNA set against Human CISD1 (NM_018464.4) - SHH264181 from Creative biogene
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Human CISD1 siRNA - orb271469 from Biorbyt
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CISD1 shRNA Plasmid (Human) - CHJ0968 from Cohesion Biosciences
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CISD1 miRNA 3'UTR clone - MiUTR3H-12212 from Creative biogene
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