PTPRN2

Gene Symbol PTPRN2
Entrez Gene 5799
Alt Symbol IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, N polypeptide 2
Other Description IAR/receptor-like protein-tyrosine phosphatase|islet cell autoantigen-related protein|phogrin|protein tyrosine phosphatase receptor pi|receptor-type tyrosine-protein phosphatase N2|tyrosine phosphatase IA-2 beta
Swissprots E9PC57 Q92932 Q9Y4I6 Q8N4I5 Q92662 Q9Y4F8
Accessions EAX04577 EAX04578 Q92932 AB002385 BAA20841 AB383870 BAG09726 AF007555 AAB63600 AL157451 CAB75665 AW292950 BC034040 AAH34040 BC071570 AAH71570 BG059906 CB850986 DB498958 DQ892399 ABM83325 DR003669 EU176514 ABW03315 U65065 AAC51643 U66702 AAC50742 U81561 AAB68603 XM_011516445 XP_011514747 XM_011516446 XP_011514748 XM_011516447 XP_011514749 XM_011516448 XP_011514750 XM_011516449 XP_011514751 NM_001308267 NP_001295196 NM_001308268 NP_001295197 NM_002847 NP_002838 NM_130842 NP_570857 NM_130843 NP_570858
Function Implicated in development of nervous system and pancreatic endocrine cells. {ECO:0000269|PubMed:8798755, ECO:0000269|PubMed:8878534}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Highest levels in brain and pancreas. Lower levels in trachea, prostate, stomach and spinal chord.
Top Pathways Type I diabetes mellitus

PTP IA-2β (N-14) - sc-30337 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTP IA-2β (N-14): sc-30337. Western blot analysis of PTP IA-2β expression in non-transfected: sc-117752 (A) and human PTP IA-2β transfected: sc-176568 (B) 293T whole cell lysates.

PTP IA-2β (M-17) - sc-30339 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTP IA-2β (M-17): sc-30339. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells and Islets of Langerhans.

PTP IA-2β (U-21) - sc-130858 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PTP IA-2β (U-21): sc-130858. Western blot analysis of PTP IA-2β expression in C6 whole cell lysate.

Anti-PTPRN2 antibody - ab168409 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-PTPRN2 antibody (ab168409) at 1/500 dilution + Human kidney tissue lysate at 50 µg

Anti-PTPRN2 antibody - ab92652 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTPRN2 antibody (ab92652) at 1/500 dilutionLane 1 : Extract from NIH/3T3 cells (without competing peptide)Lane 2 : Extract from NIH/3T3 cells (with competing peptide)Lysates/proteins at 5 µg per lane.

Anti-PTPRN2 antibody - ab157155 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTPRN2 antibody (ab157155) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extractLane 3 : HepG2 total cell extract

Anti-PTPRN2 antibody - ab55639 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55639 PTPRN2 antibody at 1ug/ml.

Anti-PTPRN2 / Phogrin Antibody (aa160-189, APC) - LS-C284894 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa160-189, FITC) - LS-C284895 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa160-189, Azide-free, HRP) - LS-C284896 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa160-189, PE) - LS-C284897 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa248-293) - LS-C313900 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus) - LS-C328386 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa160-189) - LS-C324422 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus) - LS-C101003 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
The anti-PTPIA2 beta N-term antibody is used in Western blot to detect PTPIA2 beta in C6 cell lysate.

Anti-PTPRN2 / Phogrin Antibody (aa160-189) - LS-C162316 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PTPRN2 Antibody western blot of A2058 cell line lysates (35 ug/lane). The PTPRN2 antibody detected the PTPRN2 protein (arrow).

Anti-PTPRN2 / Phogrin Antibody (aa206-255) IHC-plus™ - LS-B9261 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PTPRN2 / Phogrin antibody IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PTPRN2 / Phogrin Antibody (aa410-519) IHC-plus™ - LS-B765 from LifeSpan Bioscience

Host Chicken
Clonality Polyclonal
Anti-PTPRN2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B765 concentration 5 ug/ml.

Anti-PTPRN2 / Phogrin Antibody (aa1-17) - LS-C3171 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (aa109-126) - LS-C3170 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus, AP) - LS-C281612 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus, APC) - LS-C281613 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus, Biotin) - LS-C281614 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus, FITC) - LS-C281615 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN2 / Phogrin Antibody (N-Terminus, Azide-free, HRP) - LS-C281616 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more