PTPRN2

Gene Symbol PTPRN2
Entrez Gene 5799
Alt Symbol IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, N polypeptide 2
Other Description IAR/receptor-like protein-tyrosine phosphatase|islet cell autoantigen-related protein|phogrin|protein tyrosine phosphatase receptor pi|receptor-type tyrosine-protein phosphatase N2|tyrosine phosphatase IA-2 beta
Swissprots E9PC57 Q92932 Q9Y4I6 Q8N4I5 Q92662 Q9Y4F8
Accessions EAX04577 EAX04578 Q92932 AB002385 BAA20841 AB383870 BAG09726 AF007555 AAB63600 AL157451 CAB75665 AW292950 BC034040 AAH34040 BC071570 AAH71570 BG059906 CB850986 DB498958 DQ892399 ABM83325 DR003669 EU176514 ABW03315 U65065 AAC51643 U66702 AAC50742 U81561 AAB68603 XM_011516445 XP_011514747 XM_011516446 XP_011514748 XM_011516447 XP_011514749 XM_011516448 XP_011514750 XM_011516449 XP_011514751 NM_001308267 NP_001295196 NM_001308268 NP_001295197 NM_002847 NP_002838 NM_130842 NP_570857 NM_130843 NP_570858
Function Implicated in development of nervous system and pancreatic endocrine cells. {ECO:0000269|PubMed:8798755, ECO:0000269|PubMed:8878534}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Highest levels in brain and pancreas. Lower levels in trachea, prostate, stomach and spinal chord.
Top Pathways Type I diabetes mellitus

PTP IA-2β siRNA (h) - sc-106910 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTP IA-2β shRNA Plasmid (h) - sc-106910-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTP IA-2β shRNA (h) Lentiviral Particles - sc-106910-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTPRN2 RNAi - H00005799-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: PTPRN2 RNAi [H00005799-R01V] - Analysis of PTPRN2 over-expressed 293 cell line, cotransfected with PTPRN2 Validated Chimera RNAi or non-transfected control. Blot probed with H00005799-M08. GAPDH (36.1 kDa) used as loading control.

PTPRN2 RNAi - H00005799-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PTPRN2 RNAi - H00005799-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU082791 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0818 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0819 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0817 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN2126 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2126 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10325 from Sigma-Aldrich

Category miRNA

PTPRN2 siRNA (Human) - CRH3921 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTPRN2 RNAi - H00005799-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PTPRN2 (NM_002847.3) - SHH386792 from Creative biogene

Category siRNA
Species Reactivities Human

PTPRN2 shRNA Plasmid (Human) - CHH3921 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTPRN2 miRNA 3'UTR clone - MiUTR3H-04329 from Creative biogene

Species Reactivities Human

PTPRN2 miRNA 3'UTR clone - MiUTR3H-04330 from Creative biogene

Species Reactivities Human

PTPRN2 miRNA 3'UTR clone - MiUTR3H-04331 from Creative biogene

Species Reactivities Human
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