Gene Symbol | Rbbp5 |
---|---|
Entrez Gene | 213464 |
Alt Symbol | 4933411J24Rik, C330016J05 |
Species | Mouse |
Gene Type | protein-coding |
Description | retinoblastoma binding protein 5 |
Other Description | RBBP-5|retinoblastoma-binding protein 5 |
Swissprots | Q3TBL4 Q8BX09 Q6PAP0 Q6PFC2 Q3U3G1 |
Accessions | EDL39675 EDL39676 Q8BX09 AK016773 BAB30420 AK049247 BAC33635 AK154782 BAE32825 AK170520 AK171177 BAE42295 AK179022 AK183478 AK188299 AK195903 AK210604 AK211089 AK211823 BC030892 BC057632 AAH57632 BC060186 AAH60186 BY193756 CV562303 XM_006529357 XP_006529420 XM_006529358 XP_006529421 XM_006529359 XP_006529422 NM_172517 NP_766105 |
Function | As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. {ECO:0000269|PubMed:21335234}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Recombinant Mouse Retinoblastoma-binding protein 5(Rbbp5) - CSB-YP807425MO CSB-EP807425MO CSB-BP807425MO CSB-MP807425MO from Cusabio
|
||||||||||
RbBP5, Peptide - MBS843667 from MyBioSource
|
||||||||||
Recombinant Mouse RBBP5 Protein - RBBP5-13977M from Creative Biomart
|
||||||||||
Retinoblastoma-binding protein 5 (Rbbp5), Recombinant Protein - MBS1382166 from MyBioSource
|