Gene Symbol | CHRM3 |
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Entrez Gene | 1131 |
Alt Symbol | EGBRS, HM3 |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, muscarinic 3 |
Other Description | acetylcholine receptor, muscarinic 3|m3 muscarinic receptor|muscarinic acetylcholine receptor M3 |
Swissprots | Q9HB60 Q5VXY2 P20309 Q4QRI3 Q0VAJ8 |
Accessions | AAA70337 BAA94480 CAA33337 CAF85818 EAW70076 EAW70077 EAW70078 P20309 AF279779 AAG30036 AF385589 AAK68114 AF498917 AAM18940 AK056349 AK074575 AK095715 BC096844 AAH96844 BC121026 AAI21027 BC121027 BX099030 EU832135 ACE87485 EU832228 ACE86798 XM_005273032 XP_005273089 XM_005273034 XP_005273091 XM_011544041 XP_011542343 XM_011544042 XP_011542344 XM_011544043 XP_011542345 XM_011544044 XP_011542346 XM_011544045 XP_011542347 XM_011544046 XP_011542348 XM_011544047 XP_011542349 NM_000740 NP_000731 |
Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. {ECO:0000269|PubMed:7565628}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Regulation of actin cytoskeleton |
mAChR M3 (H-20) - sc-31486 from Santa Cruz Biotechnology
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mAChR M3 (H-210) - sc-9108 from Santa Cruz Biotechnology
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mAChR M3 (C-20) - sc-7474 from Santa Cruz Biotechnology
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mAChR M3 (L-18) - sc-31487 from Santa Cruz Biotechnology
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Anti-Muscarinic Acetylcholine Receptor M3 antibody [EPR9696] - ab154835 from Abcam
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Anti-CHRM3 / M3 Antibody (aa580-589) - LS-C9136 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (aa580-589) - LS-C9135 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (C-Terminus) - LS-C37395 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody - LS-C144026 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1422 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1423 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1421 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1424 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A5385 from LifeSpan Bioscience
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Anti-CHRM3 / M3 Antibody (C-Terminus) IHC-plus™ - LS-A5259 from LifeSpan Bioscience
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NBP2-19444 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody (580011) [Unconjugated] - MAB6378 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NB100-58978 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NLS5259 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - H00001131-A01 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NBP1-87547 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NB100-58976 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NB100-58975 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NB100-58977 from Novus Biologicals
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Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody - NB100-59004 from Novus Biologicals
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