| Gene Symbol |
CHRM3
|
| Entrez Gene |
1131
|
| Alt Symbol |
EGBRS, HM3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, muscarinic 3
|
| Other Description |
acetylcholine receptor, muscarinic 3|m3 muscarinic receptor|muscarinic acetylcholine receptor M3
|
| Swissprots |
Q9HB60 Q5VXY2 P20309 Q4QRI3 Q0VAJ8
|
| Accessions |
AAA70337 BAA94480 CAA33337 CAF85818 EAW70076 EAW70077 EAW70078 P20309 AF279779 AAG30036 AF385589 AAK68114 AF498917 AAM18940 AK056349 AK074575 AK095715 BC096844 AAH96844 BC121026 AAI21027 BC121027 BX099030 EU832135 ACE87485 EU832228 ACE86798 XM_005273032 XP_005273089 XM_005273034 XP_005273091 XM_011544041 XP_011542343 XM_011544042 XP_011542344 XM_011544043 XP_011542345 XM_011544044 XP_011542346 XM_011544045 XP_011542347 XM_011544046 XP_011542348 XM_011544047 XP_011542349 NM_000740 NP_000731
|
| Function |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. {ECO:0000269|PubMed:7565628}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Regulation of actin cytoskeleton
|
![Western Blot: Muscarinic Acetylcholine Receptor M3 Overexpression Lysate (Adult Normal) [NBL1-09175] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Muscarinic Acetylcholine Receptor M3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1711_Muscarinic%2520Acetylcholine%2520Receptor%2520M3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09175-img0002.jpg)