Gene Symbol | TMLHE |
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Entrez Gene | 55217 |
Alt Symbol | AUTSX6, BBOX2, TMLD, TMLH, TMLHED, XAP130 |
Species | Human |
Gene Type | protein-coding |
Description | trimethyllysine hydroxylase, epsilon |
Other Description | TML hydroxylase|TML-alpha-ketoglutarate dioxygenase|butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 2|epsilon-trimethyllysine 2-oxoglutarate dioxygenase|epsilon-trimethyllysine hydroxylase|trimethyllysine dioxygenase, mitochondrial |
Swissprots | Q9NVH6 A8K6M9 Q8TBT0 Q6IA90 Q5TZB5 B4E3R3 |
Accessions | EAW55873 EAW55874 EAW55875 Q9NVH6 AF373407 AAL01871 AK001589 BAA91775 AK291694 BAF84383 AK304830 BAG65575 AK310667 AM393196 CAL38074 BC009673 BC025269 AAH25269 CR457265 CAG33546 DA323339 DB174485 XM_011531182 XP_011529484 XR_247318 NM_001184797 NP_001171726 NM_018196 NP_060666 |
Function | Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML). |
Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:15754339}. |
Tissue Specificity | All isoforms, but isoform 8, are widely expressed in adult and fetal tissues. Isoform 8 is restricted to heart and skeletal muscle. {ECO:0000269|PubMed:15754339, ECO:0000269|PubMed:17408883}. |
Top Pathways | Lysine degradation |
TMLH (E-12) - sc-162335 from Santa Cruz Biotechnology
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TMLH (S-12) - sc-162336 from Santa Cruz Biotechnology
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Anti-TMLHE antibody - ab150835 from Abcam
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Anti-TMLHE / TMID Antibody (aa123-153, APC) - LS-C241898 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153, AP) - LS-C241899 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153, Biotin) - LS-C241900 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153, FITC) - LS-C241901 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153, PE) - LS-C241905 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153, Azide-free, HRP) - LS-C247086 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (FITC) - LS-C317909 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (HRP) - LS-C317910 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (Biotin) - LS-C318976 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa123-153) - LS-C325808 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody - LS-C332061 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa115-397) - LS-C185506 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa323-372) - LS-C108091 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (aa120-149) - LS-C162030 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody (C-Terminus) - LS-C170269 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody - LS-C317911 from LifeSpan Bioscience
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Anti-TMLHE / TMID Antibody - LS-C346354 from LifeSpan Bioscience
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TMLHE Antibody - NBP1-54725 from Novus Biologicals
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TMLHE Antibody - NBP1-88693 from Novus Biologicals
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TMLHE Antibody - NBP1-32144 from Novus Biologicals
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Anti-TMLHE antibody produced in rabbit - SAB2106056 from Sigma-Aldrich
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Anti-TMLHE antibody produced in rabbit - SAB2700826 from Sigma-Aldrich
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