ACER1

Gene Symbol ACER1
Entrez Gene 125981
Alt Symbol ALKCDase1, ASAH3
Species Human
Gene Type protein-coding
Description alkaline ceramidase 1
Other Description N-acylsphingosine amidohydrolase (alkaline ceramidase) 3|N-acylsphingosine amidohydrolase 3|acylsphingosine deacylase 3|alkCDase 1|alkaline CDase 1
Swissprots Q8TDN7
Accessions EAW69104 EAW69105 Q8TDN7 AF347024 AAL83822 BC112122 AAI12123 BC112124 AAI12125 CU449837 HG510303 XM_011527673 XP_011525975 NM_133492 NP_597999
Function Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo- phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Mainly expressed in epidermis. {ECO:0000269|PubMed:16477081}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

ASAH3 CRISPR/Cas9 KO Plasmid (h) - sc-414246 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 HDR Plasmid (h) - sc-414246-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 Double Nickase Plasmid (h) - sc-414246-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 Double Nickase Plasmid (h2) - sc-414246-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 CRISPR Activation Plasmid (h) - sc-414246-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 CRISPR Activation Plasmid (h2) - sc-414246-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 Lentiviral Activation Particles (h) - sc-414246-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 Lentiviral Activation Particles (h2) - sc-414246-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASAH3 siRNA (h) - sc-97592 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASAH3 shRNA Plasmid (h) - sc-97592-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASAH3 shRNA (h) Lentiviral Particles - sc-97592-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN2715 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2715 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACER1 siRNA (Human) - CRJ4825 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACER1 - MBS8231092 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACER1 (NM_133492.2) - SHH230230 from Creative biogene

Category siRNA
Species Reactivities Human

Human ACER1 siRNA - orb275326 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACER1 shRNA Plasmid (Human) - CHJ4825 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACER1 miRNA 3'UTR clone - MiUTR4H-TG10472 from Creative biogene

Species Reactivities Human
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