Gene Symbol | HSPBP1 |
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Entrez Gene | 23640 |
Alt Symbol | FES1 |
Species | Human |
Gene Type | protein-coding |
Description | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
Other Description | heat shock protein-binding protein 1|hsp70 interacting protein|hsp70-binding protein 1 |
Swissprots | B3KQP0 Q9NZL4 O95351 Q6ZNU5 B4DG11 |
Accessions | CAF86633 EAW72355 EAW72356 EAW72357 EAW72358 Q9NZL4 AB020592 BAB18742 AF093420 AAC79703 AF187859 AAF35833 AF217996 AAG17238 AI859141 AK075293 BAG52102 AK129755 AK130636 BAC85399 AK130781 AK294358 BAG57622 BC001236 AAH01236 BC002373 AAH02373 BM853303 BU630679 CR457118 CAG33399 DB500673 DQ893570 ABM84496 DQ894424 ABM85350 EU176268 ABW03719 XM_005258700 XP_005258757 XM_005258701 XP_005258758 XM_011526691 XP_011524993 NM_001130106 NP_001123578 NM_001297600 NP_001284529 NM_012267 NP_036399 |
Function | Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. {ECO:0000269|PubMed:10786638, ECO:0000269|PubMed:12651857, ECO:0000269|PubMed:15215316, ECO:0000269|PubMed:9830037}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9830037}. |
Top Pathways | Protein processing in endoplasmic reticulum |
HspBP1 (D-2) - sc-166315 from Santa Cruz Biotechnology
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HspBP1 (E-3) - sc-398319 from Santa Cruz Biotechnology
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HspBP1 (28) - sc-136354 from Santa Cruz Biotechnology
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HspBP1 (F-11) - sc-390467 from Santa Cruz Biotechnology
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HspBP1 (H-179) - sc-366142 from Santa Cruz Biotechnology
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HspBP1 (C-17) - sc-34256 from Santa Cruz Biotechnology
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HspBP1 (S-19) - sc-34255 from Santa Cruz Biotechnology
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HspBP1 (N-15) - sc-34252 from Santa Cruz Biotechnology
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Anti-HspBP1 antibody - ab3858 from Abcam
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Anti-HspBP1 antibody - ab88826 from Abcam
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Anti-HspBP1 antibody - ab115857 from Abcam
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Anti-HspBP1 antibody [2C8] - ab119184 from Abcam
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Anti-HspBP1 antibody - C-terminal - ab140353 from Abcam
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Anti-HSPBP1 Antibody (aa209-354) - LS-C294393 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (clone 1H4) - LS-C173191 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (clone 2C8) - LS-C173187 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (clone 2D1) - LS-C173192 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (clone 3E1) - LS-C173303 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (clone 1F3) - LS-C173240 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (aa84-359) - LS-C51757 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody - LS-C129609 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (aa226-275) - LS-C145388 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (aa69-97, AP) - LS-C236434 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (aa69-97, APC) - LS-C236435 from LifeSpan Bioscience
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Anti-HSPBP1 Antibody (aa69-97, Biotin) - LS-C236436 from LifeSpan Bioscience
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