Gene Symbol | HSPBP1 |
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Entrez Gene | 23640 |
Alt Symbol | FES1 |
Species | Human |
Gene Type | protein-coding |
Description | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
Other Description | heat shock protein-binding protein 1|hsp70 interacting protein|hsp70-binding protein 1 |
Swissprots | B3KQP0 Q9NZL4 O95351 Q6ZNU5 B4DG11 |
Accessions | CAF86633 EAW72355 EAW72356 EAW72357 EAW72358 Q9NZL4 AB020592 BAB18742 AF093420 AAC79703 AF187859 AAF35833 AF217996 AAG17238 AI859141 AK075293 BAG52102 AK129755 AK130636 BAC85399 AK130781 AK294358 BAG57622 BC001236 AAH01236 BC002373 AAH02373 BM853303 BU630679 CR457118 CAG33399 DB500673 DQ893570 ABM84496 DQ894424 ABM85350 EU176268 ABW03719 XM_005258700 XP_005258757 XM_005258701 XP_005258758 XM_011526691 XP_011524993 NM_001130106 NP_001123578 NM_001297600 NP_001284529 NM_012267 NP_036399 |
Function | Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. {ECO:0000269|PubMed:10786638, ECO:0000269|PubMed:12651857, ECO:0000269|PubMed:15215316, ECO:0000269|PubMed:9830037}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9830037}. |
Top Pathways | Protein processing in endoplasmic reticulum |
Human HspBP1 full length protein - ab40659 from Abcam
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Human HspBP1 full length protein - ab51233 from Abcam
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Human HspBP1 full length protein - ab95268 from Abcam
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HSPBP1 Antibody Blocking Peptide - LS-E3573 from LifeSpan Bioscience
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HSPBP1 Antibody Blocking Peptide - LS-E19787 from LifeSpan Bioscience
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HspBP1 Recombinant Protein - H00023640-P01 from Novus Biologicals
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Recombinant Human HspBP1 Protein - NBP1-44481 from Novus Biologicals
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HSPBP1-Antibody-N-term-Blocking-Peptide - BP14772a from Abgent, a WuXi AppTec company
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HSPBP1 Recombinant Protein - GTX48043-PRO from GeneTex
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HSPBP1 Protein (OPPA02146) - OPPA02146 from Aviva Systems Biology
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Human HSPBP1 protein - orb81506 from Biorbyt
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Hspbp1 Blocking Peptide - 33R-8016 from Fitzgerald
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HSPBP1 protein (His tag) - 80R-1318 from Fitzgerald
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Human HSPBP1 Protein - abx066994 from Abbexa
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HSPBP1 (1-362, His-tag) - AR09464PU-L from Acris Antibodies
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HSPBP1 (1-362, His-tag) - AR09464PU-N from Acris Antibodies
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HSPBP1 - H00023640-P01-10 from Acris Antibodies
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HSPBP1 - H00023640-P01-25 from Acris Antibodies
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HSPBP1, 1-362aa, Human, His tag, E.coli - 01-1792-1 from ARP American Research Products
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HSPBP1 Recombinant Protein - XW-RP3115 from ProSci
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HSPBP1 fusion protein - ag0282 from Proteintech Group
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HSPBP1 Human - HYPS-037 from NeoScientific
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Recombinant Human Heat Shock Protein-Binding Protein 1 - BP002310-HSP-030 from Syd Labs
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Recombinant Human Suppression of tumorigenicity protein 13 - BP002313-HSP-130 from Syd Labs
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HSPBP1, 1-362aa, Recombinant Protein - GWB-P1484B from Genway Biotech
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