Gene Symbol | DEGS2 |
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Entrez Gene | 123099 |
Alt Symbol | C14orf66, DES2, FADS8 |
Species | Human |
Gene Type | protein-coding |
Description | delta(4)-desaturase, sphingolipid 2 |
Other Description | degenerative spermatocyte homolog 2, lipid desaturase|dihydroceramide desaturase 2|sphingolipid C4-hydroxylase/delta 4-desaturase|sphingolipid delta 4 desaturase/C-4 hydroxylase|sphingolipid delta(4)-desaturase 2|sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 |
Swissprots | Q6P492 Q6QHC5 |
Accessions | EAW81688 Q6QHC5 AI380009 AY541700 AAS68362 BC063598 AAH63598 BM789564 XM_006720043 XP_006720106 NM_206918 NP_996801 |
Function | Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. {ECO:0000250|UniProtKB:Q8R2F2}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2}. |
Tissue Specificity | Highly expressed in skin, intestine and kidney. {ECO:0000269|PubMed:15063729}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
Human DEGS2 full length protein - ab165196 from Abcam
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DEGS2 Antibody Blocking Peptide - LS-E325 from LifeSpan Bioscience
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Recombinant Human DEGS2 Protein - H00123099-P01 from Novus Biologicals
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DEGS2-Antibody-C-term-Blocking-Peptide - BP10582b from Abgent, a WuXi AppTec company
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DEGS2 - H00123099-P01-10 from Acris Antibodies
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DEGS2 - H00123099-P01-25 from Acris Antibodies
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DEGS2 Control Peptide - AP05300CP-N from Acris Antibodies
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DEGS2 Peptide (OEEG01159) - OEEG01159 from Aviva Systems Biology
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Degenerative Spermatocyte Homolog 2, Peptide - MBS396380 from MyBioSource
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DEGS2 Protein - NBP2-13912PEP from Novus Biologicals
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DEGS2 Peptide, Human - M34GP04206H from Creative Peptides
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Sphingolipid delta (4)-desaturase/C4-hydroxylase DES2 (DEGS2), Recombinant Protein - MBS7089930 from MyBioSource
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Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 (DEGS2), Recombinant Protein - MBS7013693 from MyBioSource
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