DEGS2

Gene Symbol DEGS2
Entrez Gene 123099
Alt Symbol C14orf66, DES2, FADS8
Species Human
Gene Type protein-coding
Description delta(4)-desaturase, sphingolipid 2
Other Description degenerative spermatocyte homolog 2, lipid desaturase|dihydroceramide desaturase 2|sphingolipid C4-hydroxylase/delta 4-desaturase|sphingolipid delta 4 desaturase/C-4 hydroxylase|sphingolipid delta(4)-desaturase 2|sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
Swissprots Q6P492 Q6QHC5
Accessions EAW81688 Q6QHC5 AI380009 AY541700 AAS68362 BC063598 AAH63598 BM789564 XM_006720043 XP_006720106 NM_206918 NP_996801
Function Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. {ECO:0000250|UniProtKB:Q8R2F2}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2}.
Tissue Specificity Highly expressed in skin, intestine and kidney. {ECO:0000269|PubMed:15063729}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

DES2 (G-15) - sc-240312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DES2 (G-15): sc-240312. Western blot analysis of DES2 expression in human kidney tissue extract.

Anti-DEGS2 antibody - ab150952 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling DEGS2 with ab150952 at 1/20 dilution.

Anti-DEGS2 Antibody - LS-C140611 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal
Western blot of antigen immunoaffinity purified and DEGS2 antibody (LS-C140611) on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 1:400 dilution. Secondary antibody, mouse anti-rabbit HRP, used at 1:50k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes

Anti-DEGS2 Antibody (aa261-290, FITC) - LS-C234524 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody (aa261-290, PE) - LS-C234529 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody (aa261-290, Azide-free, HRP) - LS-C249816 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody (aa268-298) - LS-C320801 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody - LS-C140612 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of antigen immunoaffinity purified anti DEGS2 antibody (LS-C140612) on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 1:400 dilution. Secondary antibody, mouse anti-rabbit HRP, used at 1:50k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes

Anti-DEGS2 Antibody (aa261-290) - LS-C167353 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DEGS2 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DEGS2 Antibody (aa261-290, AP) - LS-C234520 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody (aa261-290, APC) - LS-C234521 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS2 Antibody (aa261-290, Biotin) - LS-C234523 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DEGS2 Antibody - NBP2-13912 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-DEGS2 (C-TERM) antibody produced in rabbit - SAB1301416 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DEGS2 (C-term): <B>Cat. No. SAB1301416 </B>: DEGS2 Antibody (C-term) western blot analysis in HeLa cell line lysates (35 μg/lane).

DEGS2 Antibody - C-terminal region (OAAB00599) - OAAB00599 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

DEGS2-Antibody-C-term - AP10582b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
DEGS2 Antibody (C-term) (Cat. #AP10582b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).

DEGS2 antibody - orb183050 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

DEGS2 antibody - AP05300PU-N from Acris Antibodies

Prices $470.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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