DEGS2

Gene Symbol DEGS2
Entrez Gene 123099
Alt Symbol C14orf66, DES2, FADS8
Species Human
Gene Type protein-coding
Description delta(4)-desaturase, sphingolipid 2
Other Description degenerative spermatocyte homolog 2, lipid desaturase|dihydroceramide desaturase 2|sphingolipid C4-hydroxylase/delta 4-desaturase|sphingolipid delta 4 desaturase/C-4 hydroxylase|sphingolipid delta(4)-desaturase 2|sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
Swissprots Q6P492 Q6QHC5
Accessions EAW81688 Q6QHC5 AI380009 AY541700 AAS68362 BC063598 AAH63598 BM789564 XM_006720043 XP_006720106 NM_206918 NP_996801
Function Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. {ECO:0000250|UniProtKB:Q8R2F2}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2}.
Tissue Specificity Highly expressed in skin, intestine and kidney. {ECO:0000269|PubMed:15063729}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

DES2 CRISPR/Cas9 KO Plasmid (h) - sc-410271 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 HDR Plasmid (h) - sc-410271-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 Double Nickase Plasmid (h) - sc-410271-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 Double Nickase Plasmid (h2) - sc-410271-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 CRISPR Activation Plasmid (h) - sc-410271-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 CRISPR Activation Plasmid (h2) - sc-410271-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 Lentiviral Activation Particles (h) - sc-410271-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 Lentiviral Activation Particles (h2) - sc-410271-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DES2 siRNA (h) - sc-92300 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DES2 shRNA Plasmid (h) - sc-92300-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DES2 shRNA (h) Lentiviral Particles - sc-92300-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU142461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7132 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7132 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02744 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02744

DEGS2 siRNA (Human) - CRJ4724 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEGS2 - MBS8206812 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DEGS2 (NM_206918.2) - SHH276969 from Creative biogene

Category siRNA
Species Reactivities Human

Human DEGS2 siRNA - orb275225 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEGS2 shRNA Plasmid (Human) - CHJ4724 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DEGS2 miRNA 3'UTR clone - MiUTR3H-11515 from Creative biogene

Species Reactivities Human
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