MAP3K9

Gene Symbol	MAP3K9
Entrez Gene	4293
Alt Symbol	MEKK9, MLK1, PRKE1
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 9
Other Description	mixed lineage kinase 1 (tyr and ser/thr specificity)
Swissprots	Q9H2N5 Q0D2G7 Q6EH31 A3KN85 P80192
Accessions	EAW81045 EAW81046 P80192 AF251442 AAG44591 AK091645 BAG52397 AK123430 AK294571 BAG57765 AK299727 BAG61625 AK302849 BAG64036 AY327900 AAQ23054 BC033197 AAH33197 BC040716 BC043010 BC111407 AAI11408 BC133706 AAI33707 BX648924 DB099391 XM_005267683 XP_005267740 XM_011536788 XP_011535090 XM_011536789 XP_011535091 XM_011536790 XP_011535092 XM_011536791 XP_011535093 XM_011536792 XP_011535094 XM_011536793 XP_011535095 XM_011536794 XP_011535096 NM_001284230 NP_001271159 NM_001284231 NP_001271160 NM_001284232 NP_001271161 NM_033141 NP_149132
Function	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. {ECO:0000269|PubMed:11416147, ECO:0000269|PubMed:15610029}.
Tissue Specificity	Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin. {ECO:0000269|PubMed:8477742}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MAP3K9 protein fragment - ab125554 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human MAP3K9 protein fragment - ab116944 from Abcam Category Protein Source Wheat germ Species Human

MAP3K9 / MLK1 Antibody Blocking Peptide - LS-E9368 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K9 / MLK1 Antibody Blocking Peptide - LS-E29220 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MAP3K9 / MLK1 Antibody Blocking Peptide - LS-E29221 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MAP3K9 Partial Recombinant Protein - H00004293-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MAP3K9 Peptide - P2903 from Novus Biologicals Category Peptide Species Human

MLK1-Antibody-C-term-Blocking-Peptide - BP7919a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K9 - H00004293-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAP3K9 - H00004293-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAP3K9 - P5598 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-Tagged - MAP3K9-1040H from Creative Biomart Category Protein Species Human

Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-tagged - MAP3K9-1262H from Creative Biomart Category Protein Source Insect cells Species Human

MLK1 Protein, active, 10 µg - 14-690 from EMD Millipore Category Protein Prices $329.00 Sizes 10 µg Source expressed by baculovirus in Sf21 cells

Recombinant Human Mitogen-activated protein kinase kinase kinase 9(MAP3K9) ,partial - CSB-YP013434HU CSB-EP013434HU CSB-BP013434HU CSB-MP013434HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human MAP3K9/MLK1 His - CSI13423 from Cell Science Prices $615.00 Sizes 10 μg Species Human

MAP3K9 Protein - NBP1-82781PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MLK1 Protein, active, 250 µg - 14-690M from EMD Millipore Category Protein Prices $2,441.00 Sizes 250 µg also available in 10 μg size . (cat#14-690) and in bulk (cat#14-690-K) Source expressed by baculovirus in Sf21 cells

MAP3K9-Antibody-C-term-Blocking-Peptide - BP7963b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K9-Antibody-N-term-Blocking-Peptide - BP7963a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MLK1-Blocking-Peptide-Center - BP7919c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K9 Peptide, Human - M34GP09179H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mitogen-activated protein kinase kinase kinase 9 (MAP3K9), partial, Recombinant Protein - MBS717647 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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