TGFB1I1

Gene Symbol	TGFB1I1
Entrez Gene	7041
Alt Symbol	ARA55, HIC-5, HIC5, TSC-5
Species	Human
Gene Type	protein-coding
Description	transforming growth factor beta 1 induced transcript 1
Other Description	androgen receptor coactivator 55 kDa protein|androgen receptor coactivator ARA55|androgen receptor-associated protein of 55 kDa|hydrogen peroxide-inducible clone 5 protein|hydrogen peroxide-inducible clone-5|transforming growth factor beta-1-induced transcript 1 protein
Swissprots	Q9Y2V5 Q9BPW3 O43294 B2R8D5
Accessions	ABB96286 EAW52126 EAW52127 EAW52128 EAW52129 EAW52130 O43294 AA992124 AB007836 BAA24799 AF116343 AAD22552 AK122975 AK313327 BAG36132 BC001507 AAH01507 BC001830 AAH01830 BC017288 AAH17288 BC032545 AAH32545 DA097743 NM_001042454 NP_001035919 NM_001164719 NP_001158191 NM_015927 NP_057011
Function	Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA- binding activity. {ECO:0000269|PubMed:10075738, ECO:0000269|PubMed:11463817, ECO:0000269|PubMed:11856738, ECO:0000269|PubMed:12177201, ECO:0000269|PubMed:12445807, ECO:0000269|PubMed:12700349, ECO:0000269|PubMed:15211577, ECO:0000269|PubMed:15561701, ECO:0000269|PubMed:16141357, ECO:0000269|PubMed:16624805, ECO:0000269|PubMed:16803
Subcellular Location	Cell junction, focal adhesion. Nucleus matrix. Cytoplasm, cytoskeleton. Note=Associated with the actin cytoskeleton; colocalizes with stress fibers.
Tissue Specificity	Expressed in platelets, smooth muscle and prostate stromal cells (at protein level). {ECO:0000269|PubMed:10075738, ECO:0000269|PubMed:10708479, ECO:0000269|PubMed:11311131, ECO:0000269|PubMed:12642630, ECO:0000269|PubMed:12772188, ECO:0000269|PubMed:16849583, ECO:0000269|PubMed:17166536, ECO:0000269|PubMed:17233630, ECO:0000269|PubMed:9664039}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HIC5 peptide - ab189107 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human HIC5 full length protein - ab132455 from Abcam Category Protein Source Wheat germ Species Human

Human HIC5 peptide - ab39055 from Abcam Category Peptide

ARA55 / HIC-5 Antibody Blocking Peptide - LS-E14148 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARA55 / HIC-5 Antibody Blocking Peptide - LS-E11816 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HIC5/TGFB1I1 Protein - H00007041-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TGFB1I1-Antibody-N-term-Blocking-Peptide - BP14684a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human TGFb1I1 Protein - abx069428 from Abbexa Category Protein Source E.coli Species Human

TGFB1I1 - H00007041-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TGFB1I1 - H00007041-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TGFB1I1 fusion protein - ag0868 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Transforming Growth Factor Beta 1 Induced Transcript 1 (TGFb1I1) - RPH039Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Transforming Growth Factor Beta 1 Induced Transcript 1 (TGFb1I1) - RPH039Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Transforming Growth Factor Beta 1 Induced Transcript 1 (TGFb1I1) - RPH039Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transforming growth factor beta-1-induced transcript 1 protein(TGFB1I1) - CSB-YP023447HU CSB-EP023447HU CSB-BP023447HU CSB-MP023447HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Transforming Growth Factor Beta 1 Induced Transcript 1 (TGFb1I1) - RPU144133 from Biomatik Category Protein Prices $231.00, $462.00, $693.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

TGFB1I1 Protein - abx163605 from Abbexa Category Protein Species Mouse

TGFB1I1 (transcript variant 2) - TP300761 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TGFB1I1 (transcript variant 3) - TP328899 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HIC5/TGFB1I1 Protein - NBP1-90116PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TGFB1I1 Peptide, Human - M34GP15862H from Creative Peptides Category Peptide Source Synthetic. Species Human

HIC5 Blocking Peptide - CBP7485 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Bovine

Recombinant Transforming Growth Factor Beta 1 Induced Transcript 1 (TGFb1I1) - RPU44133 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

TGFB1I1 Recombinant Protein (OPCD07383) - OPCD07383 from Aviva Systems Biology Category Protein Source E.coli Species Human

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