Gene Symbol |
CAPNS2
|
Entrez Gene |
84290
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
calpain, small subunit 2
|
Other Description |
CSS2|calcium-dependent protease small subunit 2|calpain small subunit 2
|
Swissprots |
Q9BPV4 Q96L46
|
Accessions |
EAW82830 Q96L46 AY052551 AAL02241 BC005397 AAH05397 BC006000 AAH06000 EU832656 ACE87747 HQ448149 ADQ32630 NM_032330 NP_115706
|
Function |
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}.
|