Gene Symbol | CAPNS2 |
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Entrez Gene | 84290 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | calpain, small subunit 2 |
Other Description | CSS2|calcium-dependent protease small subunit 2|calpain small subunit 2 |
Swissprots | Q9BPV4 Q96L46 |
Accessions | EAW82830 Q96L46 AY052551 AAL02241 BC005397 AAH05397 BC006000 AAH06000 EU832656 ACE87747 HQ448149 ADQ32630 NM_032330 NP_115706 |
Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}. |
CSS2 CRISPR/Cas9 KO Plasmid (h) - sc-409344 from Santa Cruz Biotechnology
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CSS2 HDR Plasmid (h) - sc-409344-HDR from Santa Cruz Biotechnology
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CSS2 Double Nickase Plasmid (h) - sc-409344-NIC from Santa Cruz Biotechnology
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CSS2 Double Nickase Plasmid (h2) - sc-409344-NIC-2 from Santa Cruz Biotechnology
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CSS2 CRISPR Activation Plasmid (h) - sc-409344-ACT from Santa Cruz Biotechnology
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CSS2 CRISPR Activation Plasmid (h2) - sc-409344-ACT-2 from Santa Cruz Biotechnology
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CSS2 Lentiviral Activation Particles (h) - sc-409344-LAC from Santa Cruz Biotechnology
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CSS2 Lentiviral Activation Particles (h2) - sc-409344-LAC-2 from Santa Cruz Biotechnology
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CSS2 siRNA (h) - sc-62160 from Santa Cruz Biotechnology
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CSS2 shRNA Plasmid (h) - sc-62160-SH from Santa Cruz Biotechnology
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CSS2 shRNA (h) Lentiviral Particles - sc-62160-V from Santa Cruz Biotechnology
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Calpain S2 RNAi - H00084290-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5351 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00318 from Sigma-Aldrich
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CAPNS2 siRNA (Human) - CRJ3415 from Cohesion Biosciences
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CAPNS2 - MBS8220935 from MyBioSource
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shRNA set against Human CAPNS2 (NM_032330.1) - SHH254429 from Creative biogene
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CAPNS2 shRNA Plasmid (Human) - CHJ3415 from Cohesion Biosciences
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CAPNS2 miRNA 3'UTR clone - MiUTR1H-01661 from Creative biogene
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