Gene Symbol | CAPNS2 |
---|---|
Entrez Gene | 84290 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | calpain, small subunit 2 |
Other Description | CSS2|calcium-dependent protease small subunit 2|calpain small subunit 2 |
Swissprots | Q9BPV4 Q96L46 |
Accessions | EAW82830 Q96L46 AY052551 AAL02241 BC005397 AAH05397 BC006000 AAH06000 EU832656 ACE87747 HQ448149 ADQ32630 NM_032330 NP_115706 |
Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}. |