PNP

Gene Symbol PNP
Entrez Gene 4860
Alt Symbol NP, PRO1837, PUNP
Species Human
Gene Type protein-coding
Description purine nucleoside phosphorylase
Other Description HEL-S-156an|epididymis secretory sperm binding protein Li 156an|inosine phosphorylase|inosine-guanosine phosphorylase|purine-nucleoside:orthophosphate ribosyltransferase
Swissprots Q15160 B2R8S5 P00491 D3DS00 Q5PZ03
Accessions AAA36460 AAV68044 EAW66458 EAW66459 P00491 AK098544 BAC05327 AK126154 AK307340 AK307364 AK313490 BAG36272 BC104206 AAI04207 BC104207 AAI04208 BC106074 AAI06075 BM193354 BU622706 CR407607 CAG28535 EU794649 ACJ13703 X00737 CAA25320 NM_000270 NP_000261
Function The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. {ECO:0000269|PubMed:2104852}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:22509282}.
Tissue Specificity Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

Human PNP gene - orb92147 from Biorbyt

Prices $306.00
Sizes 10 μg
Species Human
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