PNP

Gene Symbol PNP
Entrez Gene 4860
Alt Symbol NP, PRO1837, PUNP
Species Human
Gene Type protein-coding
Description purine nucleoside phosphorylase
Other Description HEL-S-156an|epididymis secretory sperm binding protein Li 156an|inosine phosphorylase|inosine-guanosine phosphorylase|purine-nucleoside:orthophosphate ribosyltransferase
Swissprots Q15160 B2R8S5 P00491 D3DS00 Q5PZ03
Accessions AAA36460 AAV68044 EAW66458 EAW66459 P00491 AK098544 BAC05327 AK126154 AK307340 AK307364 AK313490 BAG36272 BC104206 AAI04207 BC104207 AAI04208 BC106074 AAI06075 BM193354 BU622706 CR407607 CAG28535 EU794649 ACJ13703 X00737 CAA25320 NM_000270 NP_000261
Function The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. {ECO:0000269|PubMed:2104852}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:22509282}.
Tissue Specificity Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

PNP CRISPR/Cas9 KO Plasmid (h) - sc-404914 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP HDR Plasmid (h) - sc-404914-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP Double Nickase Plasmid (h) - sc-404914-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP Double Nickase Plasmid (h2) - sc-404914-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP CRISPR Activation Plasmid (h) - sc-404914-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP CRISPR Activation Plasmid (h2) - sc-404914-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP Lentiviral Activation Particles (h) - sc-404914-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP Lentiviral Activation Particles (h2) - sc-404914-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP siRNA (h) - sc-45991 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PNP shRNA Plasmid (h) - sc-45991-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PNP shRNA (h) Lentiviral Particles - sc-45991-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU101421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17061 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17061 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05052 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05052

PNP siRNA (Human) - CRH3231 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Purine Nucleoside Phosphorylase/PNP RNAi - H00004860-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

PNP CRISPR/Cas9 KO Plasmid (h2) - sc-404914-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP HDR Plasmid (h2) - sc-404914-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PNP shRNA Plasmid (Human) - CHH3231 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PNP miRNA 3'UTR clone - MiUTR3H-01579 from Creative biogene

Species Reactivities Human
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