KRTAP1-1
| Gene Symbol | KRTAP1-1 |
|---|---|
| Entrez Gene | 81851 |
| Alt Symbol | HB2A, KAP1.1, KAP1.1A, KAP1.1B, KAP1.6, KAP1.7, KRTAP1.1, KRTAP1A, hKAP1.7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | keratin associated protein 1-1 |
| Other Description | high sulfur keratin-associated protein 1.1|keratin associated protein 1.7|keratin associated protein 1A|keratin-associated protein 1-1|keratin-associated protein 1.1|keratin-associated protein 1.6|keratin-associated protein 1.7 |
| Swissprots | Q07627 Q96S67 A6NC32 Q96S60 |
| Accessions | CAA44937 EAW60699 Q07627 AB052868 BAB61024 AB052934 BAB61026 AB055057 BAB61031 AJ406926 CAC27565 BC069321 BC069450 BC105069 AAI05070 BC105071 AAI05072 NM_030967 NP_112229 |
| Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
| Tissue Specificity | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}. |
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![Anti-KRTAP1-1 antibody [EPR13640] (ab181375) at 1/1000 dilution + Human skin lysate at 10 µg](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_3/14132_ab181375-211342-ab181375.jpg)
