| Gene Symbol |
KRTAP1-1
|
| Entrez Gene |
81851
|
| Alt Symbol |
HB2A, KAP1.1, KAP1.1A, KAP1.1B, KAP1.6, KAP1.7, KRTAP1.1, KRTAP1A, hKAP1.7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 1-1
|
| Other Description |
high sulfur keratin-associated protein 1.1|keratin associated protein 1.7|keratin associated protein 1A|keratin-associated protein 1-1|keratin-associated protein 1.1|keratin-associated protein 1.6|keratin-associated protein 1.7
|
| Swissprots |
Q07627 Q96S67 A6NC32 Q96S60
|
| Accessions |
CAA44937 EAW60699 Q07627 AB052868 BAB61024 AB052934 BAB61026 AB055057 BAB61031 AJ406926 CAC27565 BC069321 BC069450 BC105069 AAI05070 BC105071 AAI05072 NM_030967 NP_112229
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}.
|