Gene Symbol | KRTAP1-1 |
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Entrez Gene | 81851 |
Alt Symbol | HB2A, KAP1.1, KAP1.1A, KAP1.1B, KAP1.6, KAP1.7, KRTAP1.1, KRTAP1A, hKAP1.7 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 1-1 |
Other Description | high sulfur keratin-associated protein 1.1|keratin associated protein 1.7|keratin associated protein 1A|keratin-associated protein 1-1|keratin-associated protein 1.1|keratin-associated protein 1.6|keratin-associated protein 1.7 |
Swissprots | Q07627 Q96S67 A6NC32 Q96S60 |
Accessions | CAA44937 EAW60699 Q07627 AB052868 BAB61024 AB052934 BAB61026 AB055057 BAB61031 AJ406926 CAC27565 BC069321 BC069450 BC105069 AAI05070 BC105071 AAI05072 NM_030967 NP_112229 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}. |
KRTAP1-1 CRISPR/Cas9 KO Plasmid (h) - sc-413451 from Santa Cruz Biotechnology
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KRTAP1-1 HDR Plasmid (h) - sc-413451-HDR from Santa Cruz Biotechnology
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KRTAP1-1 Double Nickase Plasmid (h) - sc-413451-NIC from Santa Cruz Biotechnology
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KRTAP1-1 Double Nickase Plasmid (h2) - sc-413451-NIC-2 from Santa Cruz Biotechnology
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KRTAP1-1 CRISPR Activation Plasmid (h) - sc-413451-ACT from Santa Cruz Biotechnology
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KRTAP1-1 CRISPR Activation Plasmid (h2) - sc-413451-ACT-2 from Santa Cruz Biotechnology
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KRTAP1-1 Lentiviral Activation Particles (h) - sc-413451-LAC from Santa Cruz Biotechnology
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KRTAP1-1 Lentiviral Activation Particles (h2) - sc-413451-LAC-2 from Santa Cruz Biotechnology
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KRTAP1-1 siRNA (h) - sc-94003 from Santa Cruz Biotechnology
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KRTAP1-1 shRNA Plasmid (h) - sc-94003-SH from Santa Cruz Biotechnology
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KRTAP1-1 shRNA (h) Lentiviral Particles - sc-94003-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11426 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11426 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02646 from Sigma-Aldrich
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KRTAP1-1 siRNA (Human) - CRJ3066 from Cohesion Biosciences
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shRNA set against Human KRTAP1-1(NM_030967.2) - SHH138683 from Creative biogene
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Human KRTAP1-1 siRNA - orb273567 from Biorbyt
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KRTAP1-1 shRNA Plasmid (Human) - CHJ3066 from Cohesion Biosciences
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KRTAP1-1 miRNA 3'UTR clone - MiUTR1H-05485 from Creative biogene
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