NR4A2

Gene Symbol NR4A2
Entrez Gene 4929
Alt Symbol HZF-3, NOT, NURR1, RNR1, TINUR
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 4, group A, member 2
Other Description NGFI-B/nur77 beta-type transcription factor homolog|T-cell nuclear receptor NOT|immediate-early response protein NOT|intermediate-early receptor protein|nuclear receptor related 1|nuclear receptor subfamily 4 group A member 2|nur related protein-1, human homolog of|orphan nuclear receptor NR4A2|orphan nuclear receptor NURR1|transcriptionally inducible nuclear receptor related 1|transcriptionally-inducible nuclear receptor
Swissprots Q53RZ2 P43354 Q6NXU0 Q16311
Accessions AAY24203 BAA75666 BAA77328 CBX47656 CBX47659 EAX11454 EAX11455 P43354 AK223625 BAD97345 AK291456 BAF84145 AK299439 BAH13033 AK309786 BC009288 AAH09288 BC066890 AAH66890 BM922519 DA093733 EU832662 ACE87753 EU832740 ACE87072 FJ643484 ACN32470 FJ643485 ACN32471 HQ692824 ADZ17335 HQ709176 ADZ17383 S77154 AAB33999 X75918 CAA53518 XM_005246621 XP_005246678 XM_005246622 XP_005246679 XM_005246623 XP_005246680 XM_006712553 XP_006712616 XM_011511246 XP_011509548 XR_427087 NM_006186 NP_006177 NM_173171 NM_173172 NM_173173
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization.
Tissue Specificity Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.

Nurr1 (F-5) - sc-376984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nurr1 (F-5): sc-376984. Western blot analysis of Nurr1 expression in SW-13 (A) and SK-N-MC (B) whole cell lysates.

Nurr1 (M-196) - sc-5568 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nurr1 (M-196): sc-5568. Western blot analysis of Nurr1 expression in non-transfected: sc-117752 (A) and human Nurr1 transfected: sc-158785 (B) 293T whole cell lysates.

Nurr1 (N-20) - sc-991 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nurr1 (N-20): sc-991. Western blot analysis of Nurr1 expression in SW-13 whole cell lysate.

Nurr1 (447C2a) - sc-81345 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Nurr1 (447C2a): sc-81345 Western Blot analysis of human recombinant Nurr1 fusion protein.

Nurr1/Nur77 (E-20) - sc-990 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nurr1/Nur77 (E-20): sc-990. Western blot analysis of Nurr1/Nur77 expression in SK-N-MC whole cell lysate.

Anti-Nurr1 antibody - ab93332 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nurr1 antibody (ab93332) at 1/1000 dilutionLane 1 : MW markerLane 2 : Human hippocampus tissue lysate at 20 µgLane 3 : Human hippocampus tissue lysate at 20 µg with immunizing peptideLane 4 : Human hippocampus tissue lysate at 20 µgSecondaryAP-conjugated secondary antibody at 1/5000 dilution

Anti-Nurr1 antibody - ab60149 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Nurr1 antibody (ab60149) at 1/100 dilution + mouse brain tissue lysate

Anti-Nurr1 antibody - ab55769 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Nurr1 antibody - ab55770 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Nurr1 antibody - ab176184 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Nurr1 antibody [447C2a] - ab54366 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 447C2a
Anti-Nurr1 antibody [447C2a] (ab54366) + immunised recombinant protein

Anti-Nurr1 antibody [N1404] - ChIP Grade - ab41917 from Abcam

Prices $394.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N1404
ChIP analysis using ab41917 binding Nurr1 in Mouse microglia whole cell lysate. Cells were cross-linked for 10 minutes with 1% formaldehyde. Samples were incubated with primary antibody (1/100 in ChIP dilution buffer - 0.01% SDS, 1.1% Triton X-100, 1.2mM EDTA, 16.7mM Tris-HCl (pH8.1), 167mM NaCl, proteanase inhibitor cocktail) for 16 hours at 4°C. Protein binding was detected using real-time PCR.Negative Control: BV2 Mouse microglia cells.Positive control: LPS treated BV2 Mouse microglia cells. See Abreview

Anti-NR4A2 / NURR1 Antibody - LS-C16919 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NR4A2 / NURR1 Antibody (N-Terminus) IHC-plus™ - LS-B4582 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NR4A2 / NURR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4582 concentration 5 ug/ml.

Anti-NR4A2 / NURR1 Antibody - LS-C73801 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-NR4A2 / NURR1 Antibody (Internal) - LS-C83741 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-NR4A2 / NURR1 Antibody (clone 447C2a) - LS-C184533 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 447C2a

Anti-NR4A2 / NURR1 Antibody (clone 2C12) - LS-C139061 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C12

Anti-NR4A2 / NURR1 Antibody (aa503-552) - LS-C110316 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NR4A2 / NURR1 antibody LS-C110316 Western blot of Fetal Liver lysate.

Anti-NR4A2 / NURR1 Antibody (C-Terminus) - LS-C80019 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.

Anti-NR4A2 / NURR1 Antibody (aa513-526) - LS-C49125 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Nurr1 staining with Nurr1 polyclonal antibody at a 1:100 dilution in adult rat brain hippocampus. Tissue was fixed in paraformaldehyde and cut into 20 micron sections.

Anti-NR4A2 / NURR1 Antibody - LS-C203153 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HEK293 cells transfected with human Nurr1 for 48 hr (lane 1) and 72hr (lane 2) using <b>Nurr1 Antibody, pAb, Rabbit</b> (1 ug/ml). The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG. Predicted Size: 80 kD. Observed Size: 80 kD.

Anti-NR4A2 / NURR1 Antibody (aa344-530) - LS-C311816 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Nurr1 antibody used in ICC/IF.

Anti-NR4A2 / NURR1 Antibody (clone 447C2a) - LS-C342570 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 447C2a
Western blot analysis of immunized recombinant protein, using anti-NR4A2 monoclonal antibody.

Anti-NR4A2 / NURR1 Antibody (aa13-42) - LS-C99204 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with NURR1 (NR4A2) antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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