| Gene Symbol |
SLC12A3
|
| Entrez Gene |
6559
|
| Alt Symbol |
NCC, NCCT, TSC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 12 (sodium/chloride transporter), member 3
|
| Other Description |
Na-Cl cotransporter|Na-Cl symporter|NaCl electroneutral thiazide-sensitive cotransporter|solute carrier family 12 member 3|thiazide-sensitive Na-Cl cotransporter|thiazide-sensitive sodium-chloride cotransporter
|
| Swissprots |
P55017 A8MSJ2 C9JNN9
|
| Accessions |
AAK38112 CCQ42979 EAW82888 EAW82889 EAW82890 EAW82891 P55017 AK223133 AK315298 BC111850 AAI11851 BF510426 U44128 AAC50355 X91220 CAA62613 XM_005256119 XP_005256176 NM_000339 NP_000330 NM_001126107 NP_001119579 NM_001126108 NP_001119580
|
| Function |
Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption. {ECO:0000269|PubMed:8528245}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Predominant in kidney.
|