Gene Symbol | SLC12A3 |
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Entrez Gene | 6559 |
Alt Symbol | NCC, NCCT, TSC |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 12 (sodium/chloride transporter), member 3 |
Other Description | Na-Cl cotransporter|Na-Cl symporter|NaCl electroneutral thiazide-sensitive cotransporter|solute carrier family 12 member 3|thiazide-sensitive Na-Cl cotransporter|thiazide-sensitive sodium-chloride cotransporter |
Swissprots | P55017 A8MSJ2 C9JNN9 |
Accessions | AAK38112 CCQ42979 EAW82888 EAW82889 EAW82890 EAW82891 P55017 AK223133 AK315298 BC111850 AAI11851 BF510426 U44128 AAC50355 X91220 CAA62613 XM_005256119 XP_005256176 NM_000339 NP_000330 NM_001126107 NP_001119579 NM_001126108 NP_001119580 |
Function | Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption. {ECO:0000269|PubMed:8528245}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominant in kidney. |
SLC12A3 peptide - ab203575 from Abcam
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SLC12A3-Antibody-N-term-Blocking-peptide - BP12230a from Abgent, a WuXi AppTec company
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SLC12A3-Antibody-Center-Blocking-Peptide - BP8971c from Abgent, a WuXi AppTec company
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SLC12A3 Blocking Peptide - 33R-1342 from Fitzgerald
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Human Na-Cl Cotransporter Protein - abx068202 from Abbexa
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Human Na-Cl Cotransporter Protein - abx068203 from Abbexa
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Na-Cl Cotransporter (NCCT), Human - 20-8917 from ARP American Research Products
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Na-Cl Cotransporter (NCCT), Human - 20-8918 from ARP American Research Products
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Na-Cl Cotransporter (NCCT), Human - 20-8919 from ARP American Research Products
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Recombinant Na-Cl Cotransporter (NCCT) - RPE361Hu01 from Uscn Life Science Inc.
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Recombinant Na-Cl Cotransporter (NCCT) - RPE361Hu02 from Uscn Life Science Inc.
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Recombinant Na-Cl Cotransporter (NCCT) - RPE361Hu01 from Cloud-clone
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Recombinant Na-Cl Cotransporter (NCCT) - RPE361Hu02 from Cloud-clone
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Na-Cl Cotransporter (NCCT) - RPU142928 from Biomatik
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Na-Cl Cotransporter (NCCT) - RPU142929 from Biomatik
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Na-Cl Cotransporter Protein (Recombinant) - abx166400 from Abbexa
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SLC12A3 (transcript variant 1) - TP321919 from Acris Antibodies
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SLC12A3 Recombinant Protein Antigen - NBP1-86376PEP from Novus Biologicals
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SLC12A3 Peptide, Human - M34GP14316H from Creative Peptides
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Recombinant Na-Cl Cotransporter (NCCT) - RPU42928 from Biomatik
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Recombinant Na-Cl Cotransporter (NCCT) - RPU50386 from Biomatik
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SLC12A3 Recombinant Protein (OPCD05589) - OPCD05589 from Aviva Systems Biology
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SLC12A3 Recombinant Protein (OPCD05590) - OPCD05590 from Aviva Systems Biology
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Na-Cl Cotransporter, Recombinant Protein - MBS2029786 from MyBioSource
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Na-Cl Cotransporter (NCCT), Recombinant Protein - MBS2011910 from MyBioSource
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