CHAF1A

Gene Symbol CHAF1A
Entrez Gene 10036
Alt Symbol CAF-1, CAF1, CAF1B, CAF1P150, P150
Species Human
Gene Type protein-coding
Description chromatin assembly factor 1, subunit A (p150)
Other Description CAF-1 subunit A|CAF-I 150 kDa subunit|CAF-I p150|CTB-50L17.7|chromatin assembly factor 1 subunit A|chromatin assembly factor I (150 kDa)|chromatin assembly factor I p150 subunit|hp150
Swissprots Q7Z7K3 Q6NXG5 Q13111 Q9UJY8
Accessions AAF04291 EAW69224 EAW69225 EAW69226 Q13111 AA576757 BC005813 BC011560 BC041606 BC052620 AAH52620 BC067093 AAH67093 BE796132 BG775588 BM826511 BQ889365 H98924 HG510268 U20979 AAA76736 XM_011527605 XP_011525907 XM_011527606 XP_011525908 XM_011527607 XP_011525909 XR_936135 NM_005483 NP_005474
Function Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). {ECO:0000250, ECO:0000269|PubMed:15327775}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10052459}. Note=DNA replication foci.

CAF-1 p150 CRISPR/Cas9 KO Plasmid (h) - sc-402472 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 HDR Plasmid (h) - sc-402472-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 Double Nickase Plasmid (h) - sc-402472-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 Double Nickase Plasmid (h2) - sc-402472-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 CRISPR Activation Plasmid (h) - sc-402472-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 CRISPR Activation Plasmid (h2) - sc-402472-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 Lentiviral Activation Particles (h) - sc-402472-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 Lentiviral Activation Particles (h2) - sc-402472-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CAF-1 p150 siRNA (h) - sc-29876 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CAF-1 p150 shRNA Plasmid (h) - sc-29876-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CAF-1 p150 shRNA (h) Lentiviral Particles - sc-29876-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHAF1A RNAi - H00010036-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU084491 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6029 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6029 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12059 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12059

CHAF1A siRNA (Human) - CRH6754 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHAF1A - MBS8215834 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHAF1A (NM_005483.2) - SHH262673 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CHAF1A(NM_005483.2) - SHG136457 from Creative biogene

Category siRNA
Species Reactivities Human

Human CHAF1A siRNA - orb267256 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHAF1A shRNA Plasmid (Human) - CHH6754 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHAF1A miRNA 3'UTR clone - MiUTR1H-02091 from Creative biogene

Species Reactivities Human
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