Gene Symbol | ADRB1 |
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Entrez Gene | 153 |
Alt Symbol | ADRB1R, B1AR, BETA1AR, RHR |
Species | Human |
Gene Type | protein-coding |
Description | adrenoceptor beta 1 |
Other Description | adrenergic, beta-1-, receptor|beta-1 adrenergic receptor|beta-1 adrenoceptor|beta-1 adrenoreceptor |
Swissprots | P08588 Q9UKG7 B0LPE2 Q9UKG8 Q5T5Y4 |
Accessions | AAD53696 AAD53697 AAG40474 AAS66983 ABY87521 CAN37601 CBX55891 EAW49485 P08588 AF272890 BC169224 AAI69224 BC169225 AAI69225 BC169226 AAI69226 J03019 AAA51667 NM_000684 NP_000675 |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. {ECO:0000269|PubMed:12391161}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. {ECO:0000250}. |
Top Pathways | cAMP signaling pathway, cGMP-PKG signaling pathway, Adrenergic signaling in cardiomyocytes, Salivary secretion, Dilated cardiomyopathy |
β1-Adrenergic Receptor Antibody - 12271 from Cell Signaling Technology
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β 1 -AR (V-19) - sc-568 from Santa Cruz Biotechnology
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β 1 -AR (A-20) - sc-567 from Santa Cruz Biotechnology
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Anti-beta 1 Adrenergic Receptor antibody - ab64996 from Abcam
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Anti-ADRB1 Antibody - LS-C96194 from LifeSpan Bioscience
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Anti-ADRB1 Antibody (aa281-330) - LS-C119382 from LifeSpan Bioscience
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Anti-ADRB1 Antibody (aa202-214) - LS-C54455 from LifeSpan Bioscience
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Anti-ADRB1 Antibody (aa428-477) - LS-C205626 from LifeSpan Bioscience
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Anti-ADRB1 Antibody (aa180-229) - LS-C110177 from LifeSpan Bioscience
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beta-1 Adrenergic R/ADRB1 Antibody - NBP1-59007 from Novus Biologicals
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beta-1 Adrenergic R/ADRB1 Antibody - NB600-978 from Novus Biologicals
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beta-1 Adrenergic R/ADRB1 Antibody - NBP2-39091 from Novus Biologicals
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ADRB1 Polyclonal Antibody - bs-0498R from Bioss
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ADRB1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0498R-A350 from Bioss
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ADRB1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0498R-A488 from Bioss
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ADRB1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0498R-A555 from Bioss
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ADRB1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0498R-A647 from Bioss
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ADRB1 Polyclonal Antibody, Cy3 Conjugated - bs-0498R-Cy3 from Bioss
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ADRB1 Polyclonal Antibody, Cy5 Conjugated - bs-0498R-Cy5 from Bioss
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ADRB1 Polyclonal Antibody, Cy5.5 Conjugated - bs-0498R-Cy5.5 from Bioss
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ADRB1 Polyclonal Antibody, Cy7 Conjugated - bs-0498R-Cy7 from Bioss
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ADRB1 Polyclonal Antibody, FITC Conjugated - bs-0498R-FITC from Bioss
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Rabbit Anti-ADRB1 Polyclonal Antibody, PE Conjugated - bs-0498R-PE from Bioss
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ADRB1 Polyclonal Antibody, Biotin Conjugated - bs-0498R-Biotin from Bioss
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ADRB1 Polyclonal Antibody, HRP Conjugated - bs-0498R-HRP from Bioss
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