PITRM1

Gene Symbol PITRM1
Entrez Gene 10531
Alt Symbol MP1, PreP
Species Human
Gene Type protein-coding
Description pitrilysin metallopeptidase 1
Other Description PreP peptidasome|metalloprotease 1 (pitrilysin family)|pitrilysin metalloproteinase 1|presequence protease, mitochondrial
Swissprots Q2M2G6 B4E0J8 Q4VBR1 C9JSL2 Q7L5Z7 Q9UPP8 B3KMJ6 O95204 Q9BSI6 Q5JRW7 Q5JRX3 Q9BVJ5 E7ES23
Accessions EAW86490 EAW86491 EAW86492 EAW86493 Q5JRX3 AA132969 AB029027 BAA83056 AF061243 AAC67244 AK001183 BAG50863 AK002061 BAG51008 AK023476 BAG51199 AK225084 AK293788 BAG57201 AK294865 BAG57968 AK299464 BAG61430 AK303406 BAG64460 AK315117 AL117409 BC001150 AAH01150 BC005025 AAH05025 BC045577 BC095422 AAH95422 BC111987 AAI11988 BC113369 AAI13370 BG720390 BI766649 BM737694 BX649017 CB529735 CD692197 CR749279 CAH18134 DA331909 XM_005252345 XP_005252402 XM_006717362 XP_006717425 XM_011519292 XP_011517594 NM_014968 NM_001242307 NP_001229236 NM_001242309 NP_001229238 NM_014889 NP_055704
Function ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. {ECO:0000269|PubMed:16849325}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:16849325}.
Tissue Specificity Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta. {ECO:0000269|PubMed:10360838}.

PITRM1 (K-19) - sc-82316 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PITRM1 (K-19): sc-82316. Western blot analysis of PITRM1 expression in HeLa (A) and HEK293 (B) whole cell lysates.

Anti-PITRM1 antibody - ab111681 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PITRM1 antibody (ab111681) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-PITRM1 antibody - ab124451 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PITRM1 antibody (ab124451) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : 293T cell lysateLane 3 : Human fetal brain lysateLane 4 : Human fetal kidney lysateLane 5 : Human fetal liver lysateLane 6 : Human fetal lung lysate

Anti-PITRM1 antibody - ab151421 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PITRM1 antibody (ab151421) at 1/1000 dilutionLane 1 : PC3 whole cell lysateLane 2 : U87 MG whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PITRM1 antibody - ab88342 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-PITRM1 antibody (ab88342) at 1 µg/ml + recombinant protein (immunogen) at 0.2 µg

Anti-PITRM1 antibody - ab170630 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PITRM1 antibody (ab170630) at 1/100 dilution + MDA-MB231 cell line lysate. at 35 µg

Anti-PITRM1 antibody - ab68502 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PITRM1 antibody (ab68502) at 1/500 dilutionLane 1 : PITRM1 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-PITRM1 / MP1 Antibody (aa544-806, FITC) - LS-C303384 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa544-806, Biotin) - LS-C297214 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa653-926, Biotin) - LS-C297329 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa88-137) - LS-C187190 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thyroid Tumor. PITRM1 antibody dilution 1.0 ug/ml.

Anti-PITRM1 / MP1 Antibody (aa653-926, FITC) - LS-C304366 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518) - LS-C163742 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PITRM1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PITRM1 antibody detected the PITRM1 protein (arrow).

Anti-PITRM1 / MP1 Antibody (aa497-526) - LS-C324061 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa544-806) - LS-C295923 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PITRM1 / MP1.

Anti-PITRM1 / MP1 Antibody (aa653-926) - LS-C295927 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PITRM1 / MP1.

Anti-PITRM1 / MP1 Antibody (aa679-925) - LS-C178905 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, AP) - LS-C223654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, APC) - LS-C223656 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, Biotin) - LS-C223657 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, Azide-free, HRP) - LS-C223659 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, PE) - LS-C223660 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PITRM1 / MP1 Antibody (aa490-518, FITC) - LS-C223658 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

PITRM1 Antibody - NBP1-81728 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PITRM1 Antibody [NBP1-81728] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

PITRM1 Antibody - NBP1-81729 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PITRM1 Antibody [NBP1-81729] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Search more