PITRM1

Gene Symbol	PITRM1
Entrez Gene	10531
Alt Symbol	MP1, PreP
Species	Human
Gene Type	protein-coding
Description	pitrilysin metallopeptidase 1
Other Description	PreP peptidasome|metalloprotease 1 (pitrilysin family)|pitrilysin metalloproteinase 1|presequence protease, mitochondrial
Swissprots	Q2M2G6 B4E0J8 Q4VBR1 C9JSL2 Q7L5Z7 Q9UPP8 B3KMJ6 O95204 Q9BSI6 Q5JRW7 Q5JRX3 Q9BVJ5 E7ES23
Accessions	EAW86490 EAW86491 EAW86492 EAW86493 Q5JRX3 AA132969 AB029027 BAA83056 AF061243 AAC67244 AK001183 BAG50863 AK002061 BAG51008 AK023476 BAG51199 AK225084 AK293788 BAG57201 AK294865 BAG57968 AK299464 BAG61430 AK303406 BAG64460 AK315117 AL117409 BC001150 AAH01150 BC005025 AAH05025 BC045577 BC095422 AAH95422 BC111987 AAI11988 BC113369 AAI13370 BG720390 BI766649 BM737694 BX649017 CB529735 CD692197 CR749279 CAH18134 DA331909 XM_005252345 XP_005252402 XM_006717362 XP_006717425 XM_011519292 XP_011517594 NM_014968 NM_001242307 NP_001229236 NM_001242309 NP_001229238 NM_014889 NP_055704
Function	ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. {ECO:0000269|PubMed:16849325}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:16849325}.
Tissue Specificity	Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta. {ECO:0000269|PubMed:10360838}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PITRM1 / MP1 Antibody Blocking Peptide - LS-E1633 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PITRM1 / MP1 Antibody Blocking Peptide - LS-E18827 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PITRM1 Protein - H00010531-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

PITRM1-Antibody-Center-Blocking-peptide - BP12390c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human MP1 Protein - abx068551 from Abbexa Category Protein Source E.coli Species Human

PITRM1 - H00010531-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Pitrilysin Metalloproteinase 1 (MP1), Human - 20-7741 from ARP American Research Products Category Protein Prices $519.00 Sizes 50 µg Source E.coli Species Human

PITRM1 fusion protein - ag0150 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PITRM1, His-tagged - PITRM1-27541TH from Creative Biomart Category Protein Source E. coli

Recombinant Pitrilysin Metalloproteinase 1 (MP1) - RPB473Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Pitrilysin Metalloproteinase 1 (MP1) - RPB473Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Pitrilysin Metalloproteinase 1 (MP1) - RPB473Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Presequence protease, mitochondrial(PITRM1) ,partial - CSB-YP692283HU CSB-EP692283HU CSB-BP692283HU CSB-MP692283HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Pitrilysin Metalloproteinase 1 (MP1) - RPU143303 from Biomatik Category Protein Prices $247.50, $495.00, $742.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

PITRM1 Protein - abx163533 from Abbexa Category Protein Species Human, Mouse, Rat

PITRM1 - TP310596 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Pitrilysin Metalloproteinase 1 (MP1), Recombinant Protein - MBS2012271 from MyBioSource Category Protein Prices $190.00, $405.00, $625.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Presequence protease, mitochondrial (PITRM1), partial, Recombinant Protein - MBS1331664 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PITRM1 Protein - NBP1-81729PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PITRM1 Recombinant Protein Antigen - NBP1-81728PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PITRM1 Peptide, Human - M34GP11824H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Pitrilysin Metalloproteinase 1 (MP1) - RPU43303 from Biomatik Category Protein Prices $198.00, $387.00, $619.00, $738.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

PITRM1 Recombinant Protein (OPCD05364) - OPCD05364 from Aviva Systems Biology Category Protein Source E.coli Species Human

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