Gene Symbol | ALDH7A1 |
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Entrez Gene | 501 |
Alt Symbol | ATQ1, EPD, PDE |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 7 family, member A1 |
Other Description | 26g turgor protein homolog|P6c dehydrogenase|alpha-AASA dehydrogenase|alpha-aminoadipic semialdehyde dehydrogenase|antiquitin-1|betaine aldehyde dehydrogenase|delta1-piperideine-6-carboxylate dehydrogenase |
Swissprots | Q6IPU8 B4DIC7 B2R669 P49419 O14619 Q9BUL4 B4DMA0 E7EPT3 |
Accessions | AAC51935 EAW48851 P49419 AI039375 AK021800 AK092507 AK123774 AK295526 BAG58439 AK297365 BAG59812 AK312459 BAG35366 AU135961 BC002515 AAH02515 BC071712 AAH71712 BC073174 AAH73174 BG680326 BU153725 CD678674 DB501575 DC375277 EU831757 ACE87275 EU831835 ACE86594 S74728 AAB31966 XM_011543417 XP_011541719 NM_001182 NP_001173 NM_001201377 NP_001188306 NM_001202404 NP_001189333 |
Function | Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. {ECO:0000269|PubMed:16491085, ECO:0000269|PubMed:20207735}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:20207735}. Nucleus {ECO:0000269|PubMed:20207735}. |
Tissue Specificity | Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}. |
Top Pathways | Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Tryptophan metabolism, Biosynthesis of amino acids, Lysine biosynthesis |
Antiquitin (A-7) - sc-514167 from Santa Cruz Biotechnology
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Antiquitin (C-4) - sc-365642 from Santa Cruz Biotechnology
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Antiquitin (D-7) - sc-376906 from Santa Cruz Biotechnology
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Antiquitin (C-18) - sc-79398 from Santa Cruz Biotechnology
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Antiquitin (H-149) - sc-292592 from Santa Cruz Biotechnology
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Antiquitin (I-20) - sc-79399 from Santa Cruz Biotechnology
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Antiquitin (Y-20) - sc-79401 from Santa Cruz Biotechnology
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Anti-ALDH7A1 Antibody (aa1-539, Biotin) - LS-C299638 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa29-539, Biotin) - LS-C299639 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa28-539, Biotin) - LS-C300754 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa1-539, FITC) - LS-C301967 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa29-539, FITC) - LS-C301966 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa28-539) - LS-C292709 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa29-539) - LS-C292710 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody - LS-C309414 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa28-539, FITC) - LS-C303678 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa1-539) - LS-C292708 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody - LS-C306202 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (C-Terminus, clone EP1935Y) IHC-plus™ - LS-B10225 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa1-539) - LS-C314308 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (N-Terminus, clone EP1934Y) IHC-plus™ - LS-B10023 from LifeSpan Bioscience
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Anti-ALDH7A1 Antibody (aa35-84) IHC-plus⢠- LS-B12007 from LifeSpan Bioscience
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ALDH7A1 Antibody - NBP2-15343 from Novus Biologicals
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ALDH7A1 Antibody - NBP1-88908 from Novus Biologicals
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ALDH7A1 Antibody - NBP2-15342 from Novus Biologicals
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