ALDH7A1

Gene Symbol ALDH7A1
Entrez Gene 501
Alt Symbol ATQ1, EPD, PDE
Species Human
Gene Type protein-coding
Description aldehyde dehydrogenase 7 family, member A1
Other Description 26g turgor protein homolog|P6c dehydrogenase|alpha-AASA dehydrogenase|alpha-aminoadipic semialdehyde dehydrogenase|antiquitin-1|betaine aldehyde dehydrogenase|delta1-piperideine-6-carboxylate dehydrogenase
Swissprots Q6IPU8 B4DIC7 B2R669 P49419 O14619 Q9BUL4 B4DMA0 E7EPT3
Accessions AAC51935 EAW48851 P49419 AI039375 AK021800 AK092507 AK123774 AK295526 BAG58439 AK297365 BAG59812 AK312459 BAG35366 AU135961 BC002515 AAH02515 BC071712 AAH71712 BC073174 AAH73174 BG680326 BU153725 CD678674 DB501575 DC375277 EU831757 ACE87275 EU831835 ACE86594 S74728 AAB31966 XM_011543417 XP_011541719 NM_001182 NP_001173 NM_001201377 NP_001188306 NM_001202404 NP_001189333
Function Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. {ECO:0000269|PubMed:16491085, ECO:0000269|PubMed:20207735}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:20207735}. Nucleus {ECO:0000269|PubMed:20207735}.
Tissue Specificity Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}.
Top Pathways Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Tryptophan metabolism, Biosynthesis of amino acids, Lysine biosynthesis

Antiquitin (A-7) - sc-514167 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Antiquitin (A-7): sc-514167. Western blot analysis of Antiquitin expression in HeLa (A), SW480 (B), Hep G2 (C), RT-4 (D) and U-251-MG (E) whole cell lysates.

Antiquitin (C-4) - sc-365642 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Antiquitin (C-4): sc-365642. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and nuclear localization.

Antiquitin (D-7) - sc-376906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Antiquitin (D-7): sc-376906. Western blot analysis of Antiquitin expression in non-transfected: sc-117752 (A) and human Antiquitin transfected: sc-111586 (B) 293T whole cell lysates.

Antiquitin (C-18) - sc-79398 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Antiquitin (C-18): sc-79398. Western blot analysis of Antiquitin expression in HeLa whole cell lysate.

Antiquitin (H-149) - sc-292592 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Antiquitin (H-149): sc-292592. Western blot analysis of Antiquitin expression in HeLa (A), Hep G2 (B) and SW480 (C) whole cell lysates.

Antiquitin (I-20) - sc-79399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Antiquitin (I-20): sc-79399. Western blot analysis of Antiquitin expression in non-transfected: sc-117752 (A) and human Antiquitin transfected: sc-111586 (B) 293T whole cell lysates.

Antiquitin (Y-20) - sc-79401 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Antiquitin (Y-20): sc-79401. Western blot analysis of Antiquitin expression in non-transfected: sc-117752 (A) and human Antiquitin transfected: sc-111586 (B) 293T whole cell lysates.

Anti-ALDH7A1 Antibody (aa1-539, Biotin) - LS-C299638 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa29-539, Biotin) - LS-C299639 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa28-539, Biotin) - LS-C300754 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa1-539, FITC) - LS-C301967 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa29-539, FITC) - LS-C301966 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa28-539) - LS-C292709 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ALDH7A1.

Anti-ALDH7A1 Antibody (aa29-539) - LS-C292710 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ALDH7A1.

Anti-ALDH7A1 Antibody - LS-C309414 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa28-539, FITC) - LS-C303678 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALDH7A1 Antibody (aa1-539) - LS-C292708 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ALDH7A1.

Anti-ALDH7A1 Antibody - LS-C306202 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ALDH7A1 Antibody (C-Terminus, clone EP1935Y) IHC-plus™ - LS-B10225 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1935Y
Anti-ALDH7A1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ALDH7A1 Antibody (aa1-539) - LS-C314308 from LifeSpan Bioscience

Prices $415.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant ALDH7A1.

Anti-ALDH7A1 Antibody (N-Terminus, clone EP1934Y) IHC-plus™ - LS-B10023 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EP1934Y
Anti-ALDH7A1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10023 dilution 1:250.

Anti-ALDH7A1 Antibody (aa35-84) IHC-plus™ - LS-B12007 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

ALDH7A1 Antibody - NBP2-15343 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALDH7A1 Antibody [NBP2-15343] - Sample (30 ug of whole cell lysate) A: Hela 7. 5% SDS PAGE ALDH7A1 antibody, antibody diluted at 1:1000.

ALDH7A1 Antibody - NBP1-88908 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALDH7A1 Antibody [NBP1-88908] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue

ALDH7A1 Antibody - NBP2-15342 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALDH7A1 Antibody [NBP2-15342] - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE; antibody diluted at 1:1000.
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