ALDH7A1

Gene Symbol ALDH7A1
Entrez Gene 501
Alt Symbol ATQ1, EPD, PDE
Species Human
Gene Type protein-coding
Description aldehyde dehydrogenase 7 family, member A1
Other Description 26g turgor protein homolog|P6c dehydrogenase|alpha-AASA dehydrogenase|alpha-aminoadipic semialdehyde dehydrogenase|antiquitin-1|betaine aldehyde dehydrogenase|delta1-piperideine-6-carboxylate dehydrogenase
Swissprots Q6IPU8 B4DIC7 B2R669 P49419 O14619 Q9BUL4 B4DMA0 E7EPT3
Accessions AAC51935 EAW48851 P49419 AI039375 AK021800 AK092507 AK123774 AK295526 BAG58439 AK297365 BAG59812 AK312459 BAG35366 AU135961 BC002515 AAH02515 BC071712 AAH71712 BC073174 AAH73174 BG680326 BU153725 CD678674 DB501575 DC375277 EU831757 ACE87275 EU831835 ACE86594 S74728 AAB31966 XM_011543417 XP_011541719 NM_001182 NP_001173 NM_001201377 NP_001188306 NM_001202404 NP_001189333
Function Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. {ECO:0000269|PubMed:16491085, ECO:0000269|PubMed:20207735}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:20207735}. Nucleus {ECO:0000269|PubMed:20207735}.
Tissue Specificity Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}.
Top Pathways Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Tryptophan metabolism, Biosynthesis of amino acids, Lysine biosynthesis

Antiquitin CRISPR/Cas9 KO Plasmid (h) - sc-417902 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin HDR Plasmid (h) - sc-417902-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin Double Nickase Plasmid (h) - sc-417902-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin Double Nickase Plasmid (h2) - sc-417902-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin CRISPR Activation Plasmid (h) - sc-417902-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin CRISPR Activation Plasmid (h2) - sc-417902-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin Lentiviral Activation Particles (h) - sc-417902-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin Lentiviral Activation Particles (h2) - sc-417902-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Antiquitin siRNA (h) - sc-72507 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Antiquitin shRNA Plasmid (h) - sc-72507-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Antiquitin shRNA (h) Lentiviral Particles - sc-72507-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU025161 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1954 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1954 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01969 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01969

ALDH7A1 siRNA (Human) - CRH0351 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALDH7A1 - MBS8217508 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ALDH7A1 (NM_001182.4) - SHH234962 from Creative biogene

Category siRNA
Species Reactivities Human

Human ALDH7A1 siRNA - orb260853 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALDH7A1 shRNA Plasmid (Human) - CHH0351 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ALDH7A1 miRNA 3'UTR clone - MiUTR3H-00162 from Creative biogene

Species Reactivities Human
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