ALDH7A1

Gene Symbol	ALDH7A1
Entrez Gene	501
Alt Symbol	ATQ1, EPD, PDE
Species	Human
Gene Type	protein-coding
Description	aldehyde dehydrogenase 7 family, member A1
Other Description	26g turgor protein homolog|P6c dehydrogenase|alpha-AASA dehydrogenase|alpha-aminoadipic semialdehyde dehydrogenase|antiquitin-1|betaine aldehyde dehydrogenase|delta1-piperideine-6-carboxylate dehydrogenase
Swissprots	Q6IPU8 B4DIC7 B2R669 P49419 O14619 Q9BUL4 B4DMA0 E7EPT3
Accessions	AAC51935 EAW48851 P49419 AI039375 AK021800 AK092507 AK123774 AK295526 BAG58439 AK297365 BAG59812 AK312459 BAG35366 AU135961 BC002515 AAH02515 BC071712 AAH71712 BC073174 AAH73174 BG680326 BU153725 CD678674 DB501575 DC375277 EU831757 ACE87275 EU831835 ACE86594 S74728 AAB31966 XM_011543417 XP_011541719 NM_001182 NP_001173 NM_001201377 NP_001188306 NM_001202404 NP_001189333
Function	Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. {ECO:0000269|PubMed:16491085, ECO:0000269|PubMed:20207735}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:20207735}. Nucleus {ECO:0000269|PubMed:20207735}.
Tissue Specificity	Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. {ECO:0000269|PubMed:8088832, ECO:0000269|PubMed:9417906}.
Top Pathways	Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Tryptophan metabolism, Biosynthesis of amino acids, Lysine biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ALDH7A1 293T Cell Transient Overexpression Lysate(Denatured) - H00000501-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ALDH7A1 overexpression lysate - LY400472 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ALDH7A1 overexpression lysate - LY432295 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ALDH7A1 293 Cell Lysate - 400481 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ALDH7A1 Overexpression Lysate (Denatured) - H00000501-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ALDH7A1 Overexpression Lysate (Native) - NBL1-07458 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Antiquitin (h): 293T Lysate - sc-111586 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

ALDH7A1 Over-expression Lysate Product - GWB-FCF172 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human ALDH7A1 Knockdown Stable Cell Line - CSC-DC000490 from Creative biogene Category Cell Line Species Human

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