Gene Symbol | STMN2 |
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Entrez Gene | 11075 |
Alt Symbol | SCG10, SCGN10 |
Species | Human |
Gene Type | protein-coding |
Description | stathmin 2 |
Other Description | neuron-specific growth-associated protein|neuronal growth-associated protein (silencer element)|stathmin-2|stathmin-like 2|superior cervical ganglia, neural specific 10|superior cervical ganglion-10 protein |
Swissprots | O14952 Q6PK68 G3V110 A8K9M2 Q93045 |
Accessions | EAW87063 EAW87064 EAW87065 Q93045 AI096716 AK091336 AK292737 BAF85426 AK297485 BAH12589 AK297594 BAH12622 AK299500 BAH13053 AK308557 AK309130 AL110174 BC006302 AAH06302 BQ069488 BT020034 AAV38837 CR456833 CAG33114 D50375 BAA23326 DC319376 DQ892719 ABM83645 DQ895968 ABM86894 S82024 AAB36428 XM_005251142 XP_005251199 NM_001199214 NP_001186143 NM_007029 NP_008960 |
Function | Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, axon. Golgi apparatus. Endosome {ECO:0000250}. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. {ECO:0000250}. |
Tissue Specificity | Neuron specific. |
Human STMN2 full length protein - ab132223 from Abcam
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Human STMN2 protein fragment - ab89354 from Abcam
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Human STMN2 protein fragment - ab117651 from Abcam
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STMN2 peptide - ab45463 from Abcam
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SCG10 / STMN2 Antibody Blocking Peptide - LS-E3865 from LifeSpan Bioscience
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SCG10 / STMN2 Antibody Blocking Peptide - LS-E25341 from LifeSpan Bioscience
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Stathmin-2/STMN2 Recombinant Protein - H00011075-P01 from Novus Biologicals
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Recombinant Human Stathmin-2/STMN2 Protein - NBP1-30285 from Novus Biologicals
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Stathmin-2/STMN2 Recombinant Protein - H00011075-Q01 from Novus Biologicals
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STMN2-Antibody-C-term-Blocking-Peptide - BP16048b from Abgent, a WuXi AppTec company
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STMN2 blocking peptide - GTX89696-PEP from GeneTex
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STMN2 Protein (OPPA02005) - OPPA02005 from Aviva Systems Biology
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Human Stathmin Like-2 protein - orb81392 from Biorbyt
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Stathmin 2 protein - 30R-1422 from Fitzgerald
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STMN2 Blocking Peptide - abx063725 from Abbexa
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STMN2 Peptide - AC21-0169-P from Abcore
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Stathmin-2 / STMN2 (39-179) - AR09305PU-L from Acris Antibodies
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Stathmin-2 / STMN2 (39-179) - AR09305PU-N from Acris Antibodies
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Stathmin-2 / STMN2 - H00011075-P01-02 from Acris Antibodies
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Stathmin-2 / STMN2 - H00011075-P01-10 from Acris Antibodies
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Stathmin-2 / STMN2 - H00011075-P01-25 from Acris Antibodies
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Stathmin-2 / STMN2 - H00011075-Q01-10 from Acris Antibodies
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Stathmin-2 / STMN2 - H00011075-Q01-25 from Acris Antibodies
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Stathmin-2, 39-179 aa, Human, E.coli - 01-2013-2 from ARP American Research Products
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STMN2 Peptide - 45-155P from ProSci
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